Clostridium difficile toxin B
- Clostridium difficile toxin B
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| cytotoxin |
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| Structure of C. difficile glucosyl transferase Toxin B showing UDP and glusose from PDB entry 2BVM [1] |
| Identifiers |
| Symbol |
ToxB |
| SCOP |
2BVM |
Clostridium difficile toxin B is a toxin generated by Clostridium difficile.[2] It is similar to Clostridium difficile Toxin A.
It is a cytotoxin.[3]
References
- ^ Reinert DJ, Jank T, Aktories K, Schulz GE. (September 2005). "Structural basis for the function of Clostridium difficile toxin B.". J Mol Biol. 351 (5): 973–81. PMID 16054646.
- ^ Planche T, Aghaizu A, Holliman R, et al. (December 2008). "Diagnosis of Clostridium difficile infection by toxin detection kits: a systematic review". Lancet Infect Dis 8 (12): 777–84. doi:10.1016/S1473-3099(08)70233-0. PMID 18977696. http://linkinghub.elsevier.com/retrieve/pii/S1473-3099(08)70233-0.
- ^ Peterson LR, Holter JJ, Shanholtzer CJ, Garrett CR, Gerding DN (August 1986). "Detection of Clostridium difficile toxins A (enterotoxin) and B (cytotoxin) in clinical specimens. Evaluation of a latex agglutination test". Am. J. Clin. Pathol. 86 (2): 208–11. PMID 3739972.
| v · d · eToxins (enterotoxin/neurotoxin/hemotoxin/cardiotoxin/phototoxin) |
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Gram negative
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| Invertebrates |
arthropod: scorpion: Charybdotoxin, Maurotoxin, Agitoxin, Margatoxin, Slotoxin, Scyllatoxin, Hefutoxin, Lq2, Birtoxin, Bestoxin, BmKAEP, Phaiodotoxin · spider: Latrotoxin ( Alpha-latrotoxin) · Stromatoxin · PhTx3
mollusca: Conotoxin · Eledoisin · Onchidal · Saxitoxin · Tetrodotoxin
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note: some toxins are produced by lower species and pass through intermediate species
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