- Enterotoxin
An enterotoxin (not to be confused with
endotoxin ) is aprotein toxin released by amicroorganism in theintestine . Enterotoxins are frequentlycytotoxic and kill cells by altering the permeability of theepithelial cells of the intestinal wall. They are mostlypore forming toxins , secreted by bacteria, that assemble to form pores incell membranes . This causes the cells to die.The death of cells that form the barrier between the intestinal lumen and the surrounding tissue causes
interstitial fluid , composed ofwater andelectrolytes to leak into the intestinal tract, causingdiarrhea .Organisms secreting enterotoxins
Examples of organisms secreting enterotoxins are: "", "
Clostridium perfringens ", "Vibrio cholerae ", "Staphylococcus aureus ", "Rotavirus" and "Yersinia enterocolitica ".ee also
*
NSP4 (rotavirus)
*Endotoxin
*Exotoxin External links
*
Wikimedia Foundation. 2010.