- Ozolinone
-
Ozolinone Systematic (IUPAC) name (2E)-[3-methyl-4-oxo-5-(piperidin-1-yl)-1,3-thiazolidin-2-ylidene]ethanoic acid Clinical data Pregnancy cat. ? Legal status Uncontrolled Routes Oral Identifiers CAS number 56784-39-5 ATC code None PubChem CID 6436036 ChemSpider 23253355 UNII 55TIT7J81D KEGG D05323 Chemical data Formula C11H16N2O3S Mol. mass 256.32 g/mol SMILES eMolecules & PubChem Ozolinone is a loop diuretic which was never marketed.[1][2][3]
It is an active metabolite of etozoline.[2]
See also
- Etozoline
References
- ^ Dictionary of organic compounds. London: Chapman & Hall. 1996. ISBN 0-412-54090-8. http://books.google.com/books?id=5S_uhYzKWisC&lpg=PA5040&dq=Ozolinone&lr&as_brr=3&pg=PA5040#v=onepage&q&f=false.
- ^ a b Greven J, Heidenreich O (October 1978). "Effects of ozolinone, a diuretic active metabolite of etozoline, on renal function. I. Clearance studies in dogs". Naunyn-Schmiedeberg's Archives of Pharmacology 304 (3): 283–7. PMID 714186.
- ^ Greven J, Beckers M, Defrain W, Meywald K, Heidenreich O (March 1980). "Studies with the optically active isomers of the new diuretic drug ozolinone. II. Inhibition by d-ozolinone of furosemide-induced diuresis". Pflügers Archiv : European Journal of Physiology 384 (1): 61–4. PMID 7189867.
Antihypertensives: diuretics (C03) Sulfonamides
(except EA)CA inhibitors (at PT)Thiazide-likes (primarily DCT)Quinethazone • Clopamide • Chlortalidone • Mefruside • Clofenamide • Metolazone • Meticrane • Xipamide • Indapamide • Clorexolone • FenquizonePotassium-sparing (at CD) ESC blockersOsmotic diuretics (PT, DL) VAs (DCT and CD) vaptans: Conivaptan • Mozavaptan • Satavaptan • Tolvaptan
tetracyclines: DemeclocyclineOther Categories:- Carboxylic acids
- Loop diuretics
- Piperidines
- Thiazolidines
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