Methemalbumin

Methemalbumin

Methemalbumin is an albumin complex consisting of albumin and heme.[1][2]

This complex gives brown color to plasma and occurs in hemolytic and hemorrhagic disorders.

Its presence in plasma is used to differentiate between hemorrhagic and edematous pancreatitis.

The Schumm test is used to differentiate intravascular haemolysis from extravascular haemolysis, as in haemolytic anaemias. A positive result is indicative of intravascular haemolysis.

References

  1. ^ MeSH Methemalbumin
  2. ^ Myara I, Myara A, Drupt F, Moatti N, Trivin F (September 1988). "Methemalbumin interference in various biochemical assays of plasma". Clin. Chem. 34 (9): 1919–20. PMID 3416455. http://www.clinchem.org/cgi/pmidlookup?view=long&pmid=3416455. 
v · d · eProteins: hemeproteins
Globins
Subunits

Alpha locus on 16: α (HBA1, HBA2) · ζ (HBZ) · θ (HBQ1) · μ (HBM)

Beta locus on 11: β (HBB) · δ (HBD) · γ (HBG1, HBG2) · ε (HBE1)
Tetramers

stages of development: HbA (α2β2) · HbA2 (α2δ2) · HbF/Fetal (α2γ2) · HbE Gower 2 (α2ε2) · HbE Gower 1 (ζ2ε2)

pathology: HbH (β4) · Barts (γ4) · HbS (α2βS2) · HbC (α2βC2) · HbE (α2βE2)
Compounds
Carboxyhemoglobin · Carbaminohemoglobin · Oxyhemoglobin/Deoxyhemoglobin · Sulfhemoglobin
Other human
Nonhuman
Other
Other
see also disorders of globin and globulin proteins

M: MYL

cell/phys (coag, heme, immu, gran), csfs

rbmg/mogr/tumr/hist, sysi/epon, btst

drug (B1/2/3+5+6), btst, trns
v · d · eProteins: Globular proteins
Serum globulins
Other
Other globulins
Albumins
Other
see also disorders of globin and globulin proteins
B proteins: BY STRUCTURE: membrane, globular (en, ca, an), fibrous

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Look at other dictionaries:

  • methemalbumin — An abnormal compound formed in the blood as a result of heme combining with plasma albumin. * * * met·hem·al·bu·min or chiefly Brit met·haem·al·bu·min .met .hēm al byü mən n an albumin complex with hematin found in plasma during diseases (as… …   Medical dictionary

  • methemalbumin — met·hem·albumin …   English syllables

  • methemalbumin — |metˌhēm+ noun Etymology: meta + hem + albumin : an albumin complex with hematin found in plasma during diseases (as blackwater fever) that are associated with extensive hemolysis …   Useful english dictionary

  • methemalbuminemia — The presence of methemalbumin in the circulating blood, indicative of intravascular hemolysis with rapid hemoglobin breakdown; found in some patients with blackwater fever or paroxysmal nocturnal hemoglobinuria; described as a means of… …   Medical dictionary

  • Cytochrome — c with heme c. Cytochromes are, in general, membrane bound hemoproteins that contain heme groups and carry out electron transport. They are found either as monomeric proteins (e.g., cytochrome c) or as subunits of bigger enzymatic complexes that… …   Wikipedia

  • Hemoglobin — Hemoglobin, human, adult (heterotetramer, (αβ)2) Structure of human hemoglobin. The protein s α and β subunits are in red and blue, and the iron containing heme groups in green. Fro …   Wikipedia

  • Myoglobin — Model of helical domains in myoglobin.[1] …   Wikipedia

  • Cytochrome P450 — Oxidase (CYP2C9) Identifiers Symbol p450 Pfam …   Wikipedia

  • Metmyoglobin — is the oxidised form of the oxygen carrying protein myoglobin. Metmyoglobin is the cause of the characteristic brown colouration of meat that occurs as it ages. In living muscle, the concentration of metmyoglobin is vanishingly small, due to the… …   Wikipedia

  • Methemoglobin — (British English: methaemoglobin) (pronounced met hemoglobin ) is a form of the oxygen carrying metalloprotein hemoglobin, in which the iron in the heme group is in the Fe3+ (ferric) state, not the Fe2+ (ferrous) of normal hemoglobin.… …   Wikipedia

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