Globulin

Globulin

Globulin is one of the two types of serum proteins, the other being albumin. This generic term encompasses a heterogeneous series of families of proteins, with larger molecules and less soluble in pure water than albumin, which migrate less than albumin during serum electrophoresis.

It is sometimes used synonymously with globular protein. However, albumin is also a globular protein, but not a globulin. All other serum globular proteins are globulins.

Protein electrophoresis is used to categorize globulins into the following four categories:
* Alpha 1 globulins
* Alpha 2 globulins
* Beta globulins
* Gamma globulins (one group of gamma globulins are immunoglobulins, that function as antibodies)

External links

* [http://www.drkaslow.com/html/proteins_-_albumin__globulins_.html Serum Proteins]
* [http://www.diaglab.vet.cornell.edu/clinpath/modules/chem/globulin.htm Cornell]
* [http://www.findarticles.com/p/articles/mi_m3225/is_1_71/ai_n8702975 Understanding and interpreting serum protein electrophoresis]


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  • Globulin — Glob u*lin, n. [From {Globule}: cf. F. globuline.] (Phisiol. Chem.) An albuminous body, insoluble in water, but soluble in dilute solutions of salt. It is present in the red blood corpuscles united with h[ae]matin to form h[ae]moglobin. It is… …   The Collaborative International Dictionary of English

  • Globulīn — (Krystallin), Proteïnsubstanz, welche sich aufgelöst in den Zellen der Krystalllinse des Auges findet; Berzelius glaubte, daß es identisch mit der coagulirbaren Substanz der rothen Blutkörperchen sei, Lehmann hat aber die Verschiedenheit beider… …   Pierer's Universal-Lexikon

  • Globulin — Globulin, Krystallin, schwefelhaltiger Protëinkörper, dem Eiweiß sehr ähnlich, in der Krystallinse und den Blutkörperchen (s. Blut) …   Herders Conversations-Lexikon

  • globulin — [glɔbylɛ̃] n. m. ÉTYM. 1846, Bescherelle; de globule. ❖ ♦ Physiol. Petit élément figuré du sang, se présentant sous forme de bâtonnet, puis de disque et jouant probablement un rôle dans la coagulation (on dit aussi hématoblaste; plaquette… …   Encyclopédie Universelle

  • globulin — ► NOUN Biochemistry ▪ any of a group of simple proteins found in blood serum and soluble in salt solution …   English terms dictionary

  • globulin — [gläb′yə lin] n. [ GLOBUL(E) + IN1] any of a group of proteins, fully soluble only in salt solutions, found in both animal and vegetable tissues: see ALBUMIN …   English World dictionary

  • globulin — /glob yeuh lin/, n. Biochem. 1. any of a group of proteins, as myosin, occurring in plant and animal tissue, insoluble in pure water but soluble in dilute salt solutions and coagulable by heat. 2. any of several groups of blood plasma proteins,… …   Universalium

  • globulin — noun Date: 1845 any of a class of simple proteins (as myosin) that are insoluble in pure water but are soluble in dilute salt solutions and that occur widely in plant and animal tissues compare alpha globulin, beta globulin, gamma globulin …   New Collegiate Dictionary

  • globulin — Name for a family of proteins precipitated from plasma (or serum) by half saturation with ammonium sulfate ( i.e., addition of an equal volume of saturated ammonium sulfate). Globulins may be further fractionated by solubility, electrophoresis,… …   Medical dictionary

  • Globulin — Globuline sind Proteinreservestoffe von Pflanzen und Proteine des Blutplasmas. Albumin jedoch gehört als einziges Blutprotein nicht zu den Globulinen. Globuline gehören zur Gruppe der Globulären Proteine. Hauptbildungsort der Globuline ist die… …   Deutsch Wikipedia

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