Prolactin cell

Prolactin cell
Prolactin cell
Code TH H3.08.02.2.00022

Lactotrophs (also known as lactotrope, mammatroph, mammotroph, epsilon acidophil, prolactin cell, and lactotropic cell) are cells in the anterior pituitary which produce prolactin in response to signals including dopamine, estrogen, progesterone and Thyrotropin-releasing hormone. Dopamine has an inhibitory effect on PRL (prolactin) secretion. Lactotrophs are acidophilic and make up about 20% of all cells in the anterior pituitary gland.

If these cells undergo neoplastic transformation, they will give rise to a prolactinoma, a prolactin-secreting pituitary adenoma.

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v · d · eHuman anatomy, endocrine system: endocrine glands (TA A11, TH H3.08, GA 11.1269)
Islets of pancreas
Hypothalamic/
pituitary axes
+parathyroid
Pituitary

Pars nervosa · Median eminence · Infundibular stalk

Pituicyte · Herring bodies

Pars intermedia · Pars tuberalis · Pars distalis

Acidophil cell (Somatotropic cell, Prolactin cell) · Basophil cell (Corticotropic cell, Gonadotropic cell, Thyrotropic cell) · Chromophobe cell

Thyroid isthmus · Lobes of thyroid gland · Pyramidal lobe of thyroid gland

Follicular cell · Parafollicular cell
Pineal gland
Pinealocyte · Corpora arenacea · Meibomian pelicle
Other
Enteroendocrine cell · Paraganglia

M: END

anat/phys/devp/horm

noco(d)/cong/tumr, sysi/epon

proc, drug (A10/H1/H2/H3/H5)
v · d · eHuman cell types / list derived primarily from ectoderm
Surface ectoderm
Trichocyte · Keratinocyte
Neural crest
glia: Schwann cell · Satellite glial cell
Digestive system
Neural tube


Lactotropes (lac = milk) are cells that actively secrete prolactin. Prolactin contributes to mammary gland maturation and the production of milk. Lactotropes work with many other hormones such as estrogen, progesterone, growth hormone, glucocorticoids, and others in mammary gland regulation. The function of lactotropes, in men, is poorly understood.***


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