- Glucose 1-phosphate
Glucose 1-phosphateGlucose 1-phosphate Identifiers CAS number 59-56-3 PubChem 65533 ChemSpider 388311 MeSH glucose-1-phosphate ChEBI CHEBI:16077 Jmol-3D images Image 1
Properties Molecular formula C6H13O9P Molar mass 260.136 1-phosphate (verify) (what is: /?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Glucose 1-phosphate (also called cori ester) is a glucose molecule with a phosphate group on the 1'-carbon.
In glycogenolysis, it is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure.
To be utilized in cellular catabolism it must first be converted to glucose 6-phosphate by the enzyme phosphoglucomutase. One reason that cells form glucose 1-phosphate instead of glucose during glycogen breakdown is that the very polar phosphorylated glucose cannot leave the cell membrane and so is marked for intracellular catabolism.
In glycogenesis, free glucose 1-phosphate can also react with UTP to form UDP-glucose, by using the enzyme UDP-glucose pyrophosphorylase. It can then return to the greater glycogen structure via glycogen synthase.
GlucoseGlucose 6-phosphate · Glucose 1-phosphate Uridine Other FructoseFructose-1-phosphate → DHAP/Glyceraldehyde → Glyceraldehyde 3-phosphate Galactose
Galactose-1-phosphate → Glucose 1-phosphate → Glucose 6-phosphate → Fructose 6-phosphate
Uridine diphosphate galactose · Uridine diphosphate glucoseGalactitol · Iditol
- Monosaccharide derivatives
- Biochemistry stubs
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