Uridine

Uridine is a molecule (known as a nucleoside) that is formed when uracil is attached to a ribose ring (also known as a ribofuranose) via a β-N₁-glycosidic bond.

If uracil is attached to a deoxyribose ring, it is known as a deoxyuridine.

Harvard researchers report that supplementation in rats with a combination of uridine and EPA/DHA omega-3 fatty acids has antidepressant activity equivalent to that of commonly prescribed antidepressant medications, such as Prozac and other SSRIs. [http://cat.inist.fr/?aModele=afficheN&cpsidt=16548265]

Sugarcane extract is rich in nucleosides, especially uridine. [http://www.thebody.com/content/art30244.html] Tomatoes also (about 500-1000 mg. of uridine per kilogram of dry matter). [http://www.aseanfood.info/Articles/11018411.pdf] clear. Brewer's yeast also contains a good amount of uridine, as yeast is high in RNA, which after digestion is broken down into uridine monophosphate. About 3 percent of yeast (dry weight) results in digestion uridine products. This assumes the usual 9% RNA content found in Brewer's yeast. However, not all commercial yeast products may contain this level of RNA. Alternatively, drinking beer also results in increased plasma uridine [http://cat.inist.fr/?aModele=afficheN&cpsidt=13973855] . The ingestion of one liter of beer results in increased plasma uridine at a level that is comparable to those reached after ingestion of CDP-choline (citicoline) (as in [http://www.ncbi.nlm.nih.gov/pubmed/10974208] , the increase is measured as a percent change relative to baseline plasma uridine).

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