Uridine diphosphate glucose

Uridine diphosphate glucose

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Section1 = Chembox Identifiers
CASNo = 133-89-1
PubChem = 8629

MeSHName = Uridine+Diphosphate+Glucose

Section2 = Chembox Properties
Formula = C15H24N2O17P2
MolarMass = 566.302 g/mol
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Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar. It is involved in glycosyltransferase reactions in metabolism.


It is used in nucleotide sugars metabolism as an activated form of glucose as a substrate for enzymes called glucosyltransferases. [cite journal |author=Rademacher T, Parekh R, Dwek R |title=Glycobiology |journal=Annu Rev Biochem |volume=57 |issue= |pages=785–838 |year=1988 |pmid=3052290 |doi=10.1146/annurev.bi.57.070188.004033]

It is a precursor of glycogen and can be converted into UDP-galactose and UDP-glucuronic acid, which can then be used as substrates by the enzymes that make polysaccharides containing galactose and glucuronic acid.

UDP-glucose can also be used as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.


UDP-glucose consists of the pyrophosphate group, the pentose sugar ribose, glucose, and the nucleobase uracil.


See also

* Nucleoside
* Nucleotide
* Oligonucleotide
* Uracil
* Uridine diphosphate

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