Uridine diphosphate glucose
- Uridine diphosphate glucose
Chembox new
ImageFile = UDP-glucose.png ImageSize =
IUPACName =
OtherNames =
Section1 = Chembox Identifiers
CASNo = 133-89-1
PubChem = 8629
SMILES = C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)
OP(=O)(O)OC3C(C(C(C(O3)CO)O)O)O)O)O
MeSHName = Uridine+Diphosphate+Glucose
Section2 = Chembox Properties
Formula = C15H24N2O17P2
MolarMass = 566.302 g/mol
Appearance =
Density =
MeltingPt =
BoilingPt =
Section3 = Chembox Hazards
Solubility =
MainHazards =
FlashPt =
Autoignition =
Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar. It is involved in glycosyltransferase reactions in metabolism.
Functions
It is used in nucleotide sugars metabolism as an activated form of glucose as a substrate for enzymes called glucosyltransferases. [cite journal |author=Rademacher T, Parekh R, Dwek R |title=Glycobiology |journal=Annu Rev Biochem |volume=57 |issue= |pages=785–838 |year=1988 |pmid=3052290 |doi=10.1146/annurev.bi.57.070188.004033]
It is a precursor of glycogen and can be converted into UDP-galactose and UDP-glucuronic acid, which can then be used as substrates by the enzymes that make polysaccharides containing galactose and glucuronic acid.
UDP-glucose can also be used as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.
Components
UDP-glucose consists of the pyrophosphate group, the pentose sugar ribose, glucose, and the nucleobase uracil.
References
See also
* Nucleoside
* Nucleotide
* DNA
* RNA
* Oligonucleotide
* Uracil
* Uridine diphosphate
Wikimedia Foundation.
2010.
Look at other dictionaries:
uridine diphosphate glucose — n a coenzyme C15H24N2O17P2 that reversibly catalyzes the formation of glucose 1 phosphate from the corresponding phosphate of galactose and that acts as a donor of glucose residues in the biosynthesis of glycogen … Medical dictionary
Uridine diphosphate glucuronic acid — Chembox new ImageFile=UDP glucuronic acid.png ImageSize=200px IUPACName= OtherNames= Section1= Chembox Identifiers CASNo=2616 64 0 PubChem=17473 SMILES=C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OC3C(C(C(C(O3)C(=O)O)O)O)O)O)O… … Wikipedia
Glucose 1-phosphate — Glucose 1 phosphate … Wikipedia
uridine diphosphoglucose — A pyrophosphate group links the 5′ position of uridine and the 1 position of d glucose; an intermediate in glycogen biosynthesis. SYN: UDPglucose. u. 4 epimerase SYN: UDPglucose 4 epimerase … Medical dictionary
uridine — ˈyu̇rəˌdēn, də̇n noun ( s) Etymology: International Scientific Vocabulary ur (I) + idine : a crystalline nucleoside C9H12N2O6 that is obtained by hydrolysis of ribonucleic acid and uridylic acid and that in the form of phosphate derivatives (as… … Useful english dictionary
UDP-glucose — (= uridine diphosphate glucose) Sugar nucleotide, active form of glucose for glucosyl transfer reactions … Dictionary of molecular biology
UDP-glucose 4-epimerase — In enzymology, an UDP glucose 4 epimerase (EC number|5.1.3.2) is an enzyme that catalyzes the chemical reaction:UDP glucose ightleftharpoons UDP galactoseHence, this enzyme has one substrate, UDP glucose, and one product, UDP galactose.This… … Wikipedia
UDP-glucose 6-dehydrogenase — In enzymology, an UDP glucose 6 dehydrogenase (EC number|1.1.1.22) is an enzyme that catalyzes the chemical reaction:UDP glucose + 2 NAD+ + H2O ightleftharpoons UDP glucuronate + 2 NADH + 2 H+The 3 substrates of this enzyme are UDP glucose, NAD+ … Wikipedia
Nucleoside-diphosphate kinase — Nucleoside diphosphate kinases (NDKs, also NDP Kinase, (poly)nucleotide kinases and nucleoside diphosphokinases) are enzymes that catalyze the exchange of phosphate groups between different nucleoside diphosphates. NDK activities maintain an… … Wikipedia
Adénosine diphosphate — Pour les articles homonymes, voir ADP. Adénosine diphosphate … Wikipédia en Français
