Dehydrogenase

A dehydrogenase (also called DHO in the literature) is an enzyme that oxidises a substrate by a reduction reaction that transfers one or more hydrides (H⁻) to an electron acceptor, usually NAD⁺/NADP⁺ or a flavin coenzyme such as FAD or FMN.

Examples

• aldehyde dehydrogenase
• acetaldehyde dehydrogenase
• alcohol dehydrogenase
• glutamate dehydrogenase (an enzyme that can convert glutamate to α-Ketoglutarate and vice versa).
• lactate dehydrogenase
• pyruvate dehydrogenase (a common enzyme that feeds the TCA Cycle in converting Pyruvate to Acetyl CoA)
• glucose-6-phosphate dehydrogenase (involved in the pentose phosphate pathway)
• glyceraldehyde-3-phosphate dehydrogenase (involved in glycolysis)
• sorbitol dehydrogenase

TCA cycle examples:

• isocitrate dehydrogenase
• alpha-ketoglutarate dehydrogenase
• succinate dehydrogenase
• malate dehydrogenase

External links

• Dehydrogenase at eMedicine Dictionary

This enzyme-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Oxidoreductases Enzyme stubs Wikimedia Foundation. 2010. Игры ⚽ Нужен реферат? Coenzyme Flavin Look at other dictionaries: dehydrogenase — ☆ dehydrogenase [dē hī′drə jən ās΄, dē΄hī drä′jə nās΄ ] n. [ DE + HYDROGEN + ASE] any oxidoreductase enzyme that acts as a catalyst, in chemical reactions involving oxidation, by the removal of hydrogen …   English World dictionary Dehydrogenase — Eine Dehydrogenase ist ein Enzym, das sein Substrat durch Abspaltung von Wasserstoffatomen oxidiert. Dehydrogenasen gehören zur Gruppe I (Oxidoreduktasen) der EC Klassifikation. Der abgespaltene Wasserstoff wird auf Cosubstrate wie NAD+ oder FAD… …   Deutsch Wikipedia dehydrogenase — noun Etymology: International Scientific Vocabulary Date: 1923 an enzyme that accelerates the removal of hydrogen from metabolites and its transfer to other substances compare succinate dehydrogenase …   New Collegiate Dictionary dehydrogenase — Class name for those enzymes that oxidize substrates by catalyzing removal of hydrogen from metabolites (hydrogen donors) and transferring it to other substances (hydrogen acceptors), which are thus reduced; most of the oxidative enzymes… …   Medical dictionary Dehydrogenase — De|hy|d|ro|ge|na|se [↑ de u. ↑ Hydrogenase], die; , n: veraltetes Syn.: Dehydrase: ein Enzym (↑ Oxidoreduktase), das die Ablösung von 2 Wasserstoff Atomen aus org. Verb. (↑ Oxidation) u. anschließend (als Hydrogenase) die Übertragung von H2 auf… …   Universal-Lexikon dehydrogenase — dehidrogenazė statusas T sritis chemija apibrėžtis Fermentas, katalizuojantis dviejų vandenilio atomų atskilimą nuo substrato. atitikmenys: angl. dehydrogenase rus. дегидрогеназа …   Chemijos terminų aiškinamasis žodynas dehydrogenase — (|)dē+ noun Etymology: International Scientific Vocabulary de + hydrogenase : any of various enzymes that accelerate the removal of hydrogen from metabolites and its transfer to other substances (as diphosphopyridine nucleotide) and thus play an… …   Useful english dictionary dehydrogenase — Enzyme that oxidizes a substrate by transferring hydrogen to an acceptor that is either NAD+/NADP+ or a flavin enzyme …   Dictionary of molecular biology dehydrogenase — /dee huy dreuh jeuh nays , nayz /, n. Biochem. an oxidoreductase enzyme that catalyzes the removal of hydrogen. [1920 25; DEHYDROGEN(ATE) + ASE] * * * …   Universalium dehydrogenase — noun Any of several enzymes that catalyze the removal of hydrogen (a proton) from biological compounds …   Wiktionary 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”