In biochemistry, a transferase is an enzyme that catalyzes the transfer of a functional group (e.g. a methyl or phosphate group) from one molecule (called the donor) to another (called the acceptor). For example, an enzyme that catalyzed this reaction would be a transferase:

:A–X + B → A + B–X

In this example, A would be the donor, and B would be the acceptor. The donor is often a coenzyme.


Proper names of transferases are formed as "donor:acceptor grouptransferase." However, other names are much more common. The common names of transferases are often formed as "acceptor grouptransferase" or "donor grouptransferase." For example, a DNA methyltransferase is a transferase that catalyzes the transfer of a methyl group to a DNA acceptor.


Transferases are classified as EC 2 in the EC number classification. Transferases can be further classified into nine subclasses:
* includes enzymes that transfer one-carbon groups (methyltransferase)
* includes enzymes that transfer aldehyde or ketone groups
* includes acyltransferases
* includes glycosyltransferases
* includes enzymes that transfer alkyl or aryl groups, other than methyl groups
* includes enzymes that transfer nitrogenous groups (transaminase)
* includes enzymes that transfer phosphorus-containing groups (phosphotransferase, including polymerase and kinase)
* includes enzymes that transfer sulfur-containing groups (sulfurtransferase and sulfotransferase)
* includes enzymes that transfer selenium-containing groups


* [ EC 2 Introduction] from the Department of Chemistry at Queen Mary, University of London

Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • Transferase — Transférase En biochimie, une transférase est une enzyme dont le rôle est de catalyser le transfert de fonctions chimiques d une molécule à une autre de manière spécifique. Les transférases sont classées EC 2 dans la classification EC. Citons… …   Wikipédia en Français

  • transférase — ● transférase nom féminin Enzyme qui catalyse spécifiquement le transfert de radicaux ou de fonctions chimiques d un donneur vers un accepteur …   Encyclopédie Universelle

  • transferase — [trans′fər ās΄, trans′fərāz΄] n. [ TRANSFER + ASE] any of a class of enzymes that act as catalysts in chemical reactions in which a radical is transferred from molecule to another …   English World dictionary

  • Transférase — En biochimie, une transférase est une enzyme dont le rôle est de catalyser le transfert d un groupe fonctionnel (par un exemple un groupe éthyle ou phosphate) d une molécule (appelée donneur) à une autre (appelée accepteur). Par exemple, une… …   Wikipédia en Français

  • Transferase — Transferasen (von lat. lateinisch: transferre – hinübertragen) sind Enzyme der zweiten Enzymklasse laut der systematischen Nomenklatur der Enzymkommission der International Union of Biochemistry (IUB) und katalysieren die Übertragung einer… …   Deutsch Wikipedia

  • transferase — transferazė statusas T sritis chemija apibrėžtis Fermentas, katalizuojantis funkcinių grupių pernašą. atitikmenys: angl. transferase rus. трансфераза …   Chemijos terminų aiškinamasis žodynas

  • transferase — noun Date: 1948 an enzyme that promotes transfer of a group from one molecule to another …   New Collegiate Dictionary

  • transferase — A suffix to the name of an enzyme indicating that it transfers a specific grouping from one molecule to another; eg. acyl transferases transfer acyl groups …   Dictionary of molecular biology

  • transferase — /trans feuh rays , rayz /, n. Biochem. any of the class of enzymes, as the transaminases that catalyze the transfer of an organic group from one compound to another. [1945 50; TRANSFER + ASE] * * * ▪ enzyme       any one of a class of more than… …   Universalium

  • transferase — noun Any of various enzymes that catalyze the transfer of a functional group, such as amine or phosphate from one molecule to another …   Wiktionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”