List of enzymes

This article is a list of enzymes, sorted by their respective sub-categories and EC number.

See also:
* List of EC numbers
* List of EC numbers (EC 1)
* List of EC numbers (EC 2)
* List of EC numbers (EC 3)
* List of EC numbers (EC 4)
* List of EC numbers (EC 5)
* List of EC numbers (EC 6)

(EC 1) (Oxidoreductase)

*Dehydrogenase
*Luciferase
*DMSO reductase

(act on the CH-OH group of donors)

* (with NAD⁺ or NADP⁺ as acceptor)
**Alcohol dehydrogenase (NAD) EC number|1.1.1.1
**Alcohol dehydrogenase (NADP) EC number|1.1.1.2
**Homoserine dehydrogenase EC number|1.1.1.3
**Aminopropanol oxidoreductase EC number|1.1.1.4
**Diacetyl reductase EC number|1.1.1.5
**Glycerol dehydrogenase EC number|1.1.1.6
**Propanediol phosphate dehydrogenase EC number|1.1.1.7
**glycerol-3-phosphate dehydrogenase (NAD) EC number|1.1.1.8
**D-xylulose reductase EC number|1.1.1.9
**L-xylulose reductase EC number|1.1.1.10
**Lactate dehydrogenase EC number|1.1.1.27
**Malate dehydrogenase EC number|1.1.1.37
**Isocitrate dehydrogenase EC number|1.1.1.42
**HMG-CoA reductase EC number|1.1.1.88
* (with a cytochrome as acceptor)
* (with oxygen as acceptor)
**Glucose oxidase EC number|1.1.3.4
**L-gulonolactone oxidase EC number|1.1.3.8
**Xanthine oxidase EC number|1.1.3.32
* (with a disulfide as acceptor)
* (with a quinone or similar compound as acceptor)
* (with other acceptors)

(act on the aldehyde or oxo group of donors)

*
**Acetaldehyde dehydrogenase EC number|1.2.1.10
**Glyceraldehyde 3-phosphate dehydrogenase EC number|1.2.1.12
**Pyruvate dehydrogenase EC number|1.2.1.51
*
**Oxoglutarate dehydrogenase EC number|1.2.4.2

(act on the CH-CH group of donors)

* (with NAD⁺ or NADP⁺ as acceptor)
**Biliverdin reductase EC number|1.3.1.24
* (with a cytochrome as acceptor)
* (with oxygen as acceptor)
**Protoporphyrinogen oxidase EC number|1.3.3.4
* (with a quinone or similar compound as acceptor)
* (with an iron-sulfur protein as acceptor)
* (with other acceptors)

(act on the CH-NH₂ group of donors)

*
**Monoamine oxidase EC number|1.4.3.4

(act on CH-NH group of donors)

* (with NAD⁺ or NADP⁺ as acceptor)
**Dihydrofolate reductase EC number|1.5.1.3
**Methylenetetrahydrofolate reductase EC number|1.5.1.20
* (with oxygen as acceptor)
**Sarcosine oxidase EC number|1.5.3.1
**Dihydrobenzophenanthridine oxidase EC number|1.5.3.12
* (with a disulfide as acceptor)
* (with a quinone or similar compound as acceptor)
* (with an iron-sulfur protein as acceptor)
* (with a flavin as acceptor)
* (with other acceptors)

(act on NADH or NADPH)

* (with NAD⁺ or NADP⁺ as acceptor)
* (with a cytochrome as acceptor)
* (with oxygen as acceptor)
* (with a disulfide as acceptor)
* (with a quinone or similar compound as acceptor)
**NADH dehydrogenase EC number|1.6.5.3
* (with a nitrogenous group as acceptor)
* (with an iron-sulfur protein as acceptor)
* (with a flavin as acceptor)
* (with other acceptors)

(act on other nitrogenous compounds as donors)

* (with NAD⁺ or NADP⁺ as acceptor)
* (with a cytochrome as acceptor)
* (with oxygen as acceptor)
**Urate oxidase EC number|1.7.3.3
* (with an iron-sulfur protein as acceptor)
* (with other acceptors)

(act on a sulfur group of donors)

* (with NAD⁺ or NADP⁺ as acceptor)
**Glutathione reductase EC number|1.8.1.7
**Thioredoxin reductase EC number|1.8.1.9
* (with a cytochrome as acceptor)
* (with oxygen as acceptor)
**Sulfite oxidase EC number|1.8.3.1
* (with a disulfide as acceptor)
* (with a quinone or similar compound as acceptor)
* (with a sulfur group as acceptor)
* (with an iron-sulfur protein as acceptor)
* (with other, known, acceptors)
* (with other acceptors)

(act on a heme group of donors)

* (with oxygen as acceptor)
**Cytochrome c oxidase EC number|1.9.3.1
* (with a nitrogenous as acceptor)
*
**Deiodinase EC number|1.97.1.10
* (with other acceptors)

(act on diphenols and related substances as donors)

*(with NAD⁺ or NADP⁺ as acceptor)
* (with a cytochrome as acceptor)
**Coenzyme Q - cytochrome c reductase EC number|1.10.2.2
* (with oxygen as acceptor)
**Catechol oxidase EC number|1.10.3.1
**Laccase EC number|1.10.3.2
* (with other acceptors)

(act on peroxide as an acceptor -- peroxidases)

* (peroxidases)
**Cytochrome c peroxidase EC number|1.11.1.5
**Catalase EC number|1.11.1.6
**Myeloperoxidase EC number|1.11.1.7
**Thyroid peroxidase EC number|1.11.1.8
**Glutathione peroxidase EC number|1.11.1.9

(act on hydrogen as a donor)

* (with NAD⁺ or NADP⁺ as acceptor)
* (with a cytochrome as acceptor)
* (with a quinone or similar compound as acceptor)
* (with an iron-sulfur protein as acceptor)
* (with other known acceptors)
* (with other acceptors)

(act on single donors with incorporation of molecular oxygen)

* (With incorporation of two atoms of oxygen)
**4-hydroxyphenylpyruvate dioxygenase (EC number|1.13.11.27)
* (With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases))
**Renilla luciferase EC number|1.13.12.5
**Cypridina luciferase EC number|1.13.12.6
**Firefly luciferase EC number|1.13.12.7
**Watasenia luciferase EC number|1.13.12.8
**Oplophorus luciferase EC number|1.13.12.13

(act on paired donors with incorporation of molecular oxygen)

*Cytochrome P450 oxidase
*
**Aromatase EC number|1.14.14.1
**CYP2D6 EC number|1.14.14.1
**CYP2E1 EC number|1.14.14.1
**CYP3A4 EC number|1.14.14.1
**Cytochrome P450 oxidase
*
**Nitric oxide dioxygenase
*
**Nitric oxide synthase EC number|1.14.13.39
*
**Aromatase EC number|1.14.14.1
**CYP2D6 EC number|1.14.14.1
**CYP2E1 EC number|1.14.14.1
**CYP3A4 EC number|1.14.14.1
*
**Phenylalanine hydroxylase EC number|1.14.16.1
*
**Tyrosinase EC number|1.14.18.1

(act on superoxide radicals as acceptors)

*
**Superoxide dismutase EC number|1.15.1.1

(oxidize metal ions)

*
**Ceruloplasmin EC number|1.16.3.1

(act on CH or CH₂ groups)

(act on iron-sulfur proteins as donors)

*
**Nitrogenase EC number|1.18.6.1

(act on reduced flavodoxin as donor)

(act on phosphorus or arsenic as donors)

(act on X-H and Y-H to form an X-Y bond)

(other oxidoreductases)

(EC 2) (Transferase)

* Glutathione S-transferase

(transfer one-carbon groups, Methylase)

*
**Catechol-O-methyl transferase EC number|2.1.1.6
**DNA methyltransferase EC number|2.1.1.72, EC number|2.1.1.113, EC number|2.1.1.37
**Histone methyltransferase EC number|2.1.1.43, EC number|2.1.1.125
*
**ATCase EC number|2.1.3.2
**Ornithine transcarbamoylase EC number|2.1.3.3

(transfer aldehyde or ketone groups)

(acyltransferases)

*
**Aminolevulinic acid synthase EC number|2.3.1.37
**Choline acetyltransferase EC number|2.3.1.6
*
**Factor XIII EC number|2.3.2.13
**Gamma glutamyl transpeptidase EC number|2.3.2.2
**Transglutaminase EC number|2.3.2.13

(glycosyltransferases)

*
**Hypoxanthine-guanine phosphoribosyltransferase EC number|2.4.2.8

*
**Thiaminase EC number|2.5.1.2

(transfer alkyl or aryl groups, other than methyl groups)

(transfer nitrogenous groups)

*
**Alanine transaminase EC number|2.6.1.2
**Aspartate transaminase EC number|2.6.1.1

(transfer phosphorous-containing groups)

(transfer sulfur-containing groups)

(transfer selenium-containing groups)

(EC 3) (Hydrolase)

* Hydrolytic enzyme

(act on ester bonds)

*Nuclease
*Endonuclease
*Exonuclease
*
**Acid hydrolase
**Phospholipase A (EC number|3.1.1.4)
**Acetylcholinesterase (EC number|3.1.1.7)
**Cholinesterase (EC number|3.1.1.8)
**Lipoprotein lipase (EC number|3.1.1.34)
*
**Ubiquitin carboxy-terminal hydrolase L1 (EC number|3.1.2.15)
*
**Phosphatase
**Alkaline phosphatase (EC number|3.1.3.1)
**Fructose bisphosphatase (EC number|3.1.3.11)
*
**Phospholipase C (EC number|3.1.4.3)
**CGMP specific phosphodiesterase type 5 (EC number|3.1.4.17)
**Phospholipase D (EC number|3.1.4.50)
*
**Restriction enzyme Type 1 (EC number|3.1.21.3)
**Deoxyribonuclease I (EC number|3.1.21.1)
*
**RNase H (EC number|3.1.26.4)
*
**Ribonuclease

(act on sugars - glycosylases)

*
**Amylase (EC number|3.2.1.1)
**Sucrase (EC number|3.2.1.10)
**Chitinase (EC number|3.2.1.14)
**Lysozyme (EC number|3.2.1.17)
**Maltase (EC number|3.2.1.20)
**Lactase (EC number|3.2.1.23)
**Beta-galactosidase (EC number|3.2.1.23)
**Hyaluronidase (EC number|3.2.1.35)

(act on ether bonds)

(act on peptide bonds - Peptidase)

*
**Alanine aminopeptidase
*
**Angiotensin converting enzyme
*
**Serine protease
**Chymotrypsin (EC number|3.4.21.1)
**Trypsin (EC number|3.4.21.4)
**Thrombin (EC number|3.4.21.5)
**Factor X (EC number|3.4.21.6)
**Plasmin (EC number|3.4.21.7)
**Acrosin (EC number|3.4.21.10)
**Factor VII (EC number|3.4.21.21)
**Factor IX (EC number|3.4.21.22)
**Factor XI (EC number|3.4.21.27)
**Elastase (EC number|3.4.21.37)
**Factor XII (EC number|3.4.21.38)
**Tissue plasminogen activator (EC number|3.4.21.68)
**Protein C (EC number|3.4.21.69)
*
**Separase (EC number|3.4.22.49)
*
**Pepsin (EC number|3.4.23.1)
**Rennet (EC number|3.4.23.4)
**Renin (EC number|3.4.23.15)
**Trypsinogen (EC number|3.4.23.18) and (20/21/23/24/26)
**Plasmepsin (EC number|3.4.23.39)
*
**Matrix metalloproteinase (EC number|3.4.24.7)
*
**Metalloendopeptidase

(act on carbon-nitrogen bonds, other than peptide bonds)

* (In linear amides)
**Urease (EC number|3.5.1.5)
* (In cyclic amides)
**Beta-lactamase (EC number|3.5.2.6)
* (In linear amidines)
**Arginase (EC number|3.5.3.1)
* (In cyclic amidines)
**Adenosine deaminase (EC number|3.5.4.4)
**GTP cyclohydrolase I (EC number|3.5.4.16)
* (In nitriles)
**Nitrilase (EC number|3.5.5.1)

(act on acid anhydrides)

*
**Helicase
**DnaB helicase
**RecQ helicase
*
**ATPase
**NaKATPase (EC number|3.6.3.9)
**ATP synthase (EC number|3.6.3.14)

(act on carbon-carbon bonds)

* Kynureninase EC number|3.7.1.3

(act on halide bonds)

(act on phosphorus-nitrogen bonds)

(act on sulfur-nitrogen bonds)

(act on carbon-phosphorus bonds)

(act on sulfur-sulfur bonds)

(act on carbon-sulfur bonds)

(EC 4) (Lyase)

(carbon-carbon lyases)

*
**Ornithine decarboxylase (EC number|4.1.1.17)
**Uridine monophosphate synthetase (EC number|4.1.1.23)
**Aromatic-L-amino-acid decarboxylase (EC number|4.1.1.28)
**RubisCO (EC number|4.1.1.39)

(carbon-oxygen lyases)

*
**Carbonic anhydrase (EC number|4.2.1.1)
**Tryptophan synthase (EC number|4.2.1.20)

(carbon-nitrogen lyases)

(carbon-sulfur lyases)

(carbon-halide lyases)

(phosphorus-oxygen lyases)

*
**Adenylate cyclase (EC number|4.6.1.1)
**Guanylate cyclase (EC number|4.6.1.2)

(EC 5) (Isomerase)

(racemases and epimerases)

(cis-trans-isomerases)

(intramolecular oxidoreductases)

*
**Enoyl CoA isomerase (EC number|5.3.3.8)
*
**Protein disulfide isomerase (EC number|5.3.4.1)

(intramolecular transferases -- mutases)

*
**Phosphoglucomutase (EC number|5.4.2.2)

(intramolecular lyases)

(other isomerases)

*
**Topoisomerase (type I: EC number|5.99.1.2, type II: EC number|5.99.1.3)

(EC 6) (Ligase)

(form carbon-oxygen bonds)

(form carbon-sulfur bonds)

(form carbon-nitrogen bonds)

* Glutamine synthetase (EC number|6.3.1.2)
* Argininosuccinate synthetase (EC number|6.3.4.5)
* CTP synthase (EC number|6.3.4.2)

(form carbon-carbon bonds)

* Pyruvate carboxylase (EC number|6.4.1.1)
* Acetyl-CoA carboxylase (EC number|6.4.1.2)

(form phosphoric ester bonds)

DNA ligase (EC number|6.5.1.1)

(form nitrogen-metal bonds)