- 2,4-Dichlorobenzyl alcohol
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2,4-Dichlorobenzyl alcohol (2,4-Dichlorophenyl)methanolOther namesDybenal
Rapidosept
Myacide SPIdentifiers CAS number 1777-82-8 PubChem 15684 ChemSpider 14918 ChEBI CHEBI:48220 Jmol-3D images Image 1
Image 2- C1=CC(=C(C=C1Cl)Cl)CO
Clc1cc(Cl)ccc1CO
Properties Molecular formula C7H6Cl2O Molar mass 177.03 g/mol Melting point 57-60 °C
Boiling point 150 °C (25 mmHg)
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)Infobox references 2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections. It is a common ingredient in throat lozenges such as Strepsils/Gorpils. A low-pH throat lozenge containing dichlorobenzyl alcohol (1.2 mg) and amylmetacresol (600μg) has been found to inactivate Respiratory syncytial virus and SARS-Cov, but not adenovirus or rhinovirus [1]. A dentifrice containing 10% sodium benzoate and 0.3% dichlorobenzyl alcohol maintains antimicrobial activity for 5–10 minutes after brushing[2].
References
- ^ Oxford JS, Lambkin R, Gibb I, Balasingam S, Chan C, Catchpole A (2005). "A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV". Antiviral chemistry and chemotherapy 16 (2): 129–34. PMID 15889535.
- ^ Ostergaard E (1994). "Evaluation of the antimicrobial effects of sodium benzoate and dichlorobenzyl alcohol against dental plaque microorganisms. An in vitro study.". Acta Odontol Scand. 52 (6): 335–45. doi:10.3109/00016359409029031. PMID 7887143.
Throat preparations (R02) Antiseptics Acriflavinium chloride • Ambazone • Benzalkonium • Benzethonium • Cetrimonium (bromide/chloride) • Cetylpyridinium • Chlorhexidine • Chlorquinaldol • Dequalinium • Dichlorobenzyl alcohol • Hexamidine • Hexylresorcinol • Myristyl-benzalkonium • Oxyquinoline • Phenol • Povidone-iodineAntibiotics Local anesthetics Other This article about an aromatic compound is a stub. You can help Wikipedia by expanding it. - C1=CC(=C(C=C1Cl)Cl)CO