- NCAPG2
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Non-SMC condensin II complex, subunit G2 Identifiers Symbols NCAPG2; CAP-G2; FLJ20311; LUZP5; MTB; hCAP-G2 External IDs OMIM: 608532 MGI: 1923294 HomoloGene: 9820 GeneCards: NCAPG2 Gene Gene Ontology Molecular function • binding
• methylated histone residue bindingCellular component • nucleus
• nucleolusBiological process • inner cell mass cell proliferation
• cell cycle
• mitosis
• chromosome condensation
• cell divisionSources: Amigo / QuickGO RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 54892 76044 Ensembl ENSG00000146918 ENSMUSG00000042029 UniProt Q86XI2 Q3UU24 RefSeq (mRNA) NM_017760 NM_133762.3 RefSeq (protein) NP_060230 NP_598523.3 Location (UCSC) Chr 7:
158.42 – 158.5 MbChr 12:
117.64 – 117.7 MbPubMed search [1] [2] Condensin-2 complex subunit G2 (CAP-G2) also known as chromosome-associated protein G2 (CAP-G2) or leucine zipper protein 5 (LUZP5) is a protein that in humans is encoded by the NCAPG2 gene.[1][2] CAP-G2 is a subunit of condensin II, a large protein complex involved in chromosome condensation.
References
- ^ Ono T, Losada A, Hirano M, Myers MP, Neuwald AF, Hirano T (Oct 2003). "Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells". Cell 115 (1): 109–21. doi:10.1016/S0092-8674(03)00724-4. PMID 14532007.
- ^ "Entrez Gene: NCAPG2 non-SMC condensin II complex, subunit G2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54892.
Further reading
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2882961.
- Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Smith ED, Xu Y, Tomson BN, et al. (2004). "More than blood, a Novel Gene Required for Mammalian Postimplantation Development". Mol. Cell. Biol. 24 (3): 1168–73. doi:10.1128/MCB.24.3.1168-1173.2004. PMC 321451. PMID 14729962. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=321451.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1356129.
- Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1459365.
Structures of the cell nucleus / nuclear protein Envelope (membrane)/
nuclear laminaNucleolus Other Chromatin · Dot (PML body) · Paraspeckle
SMC protein: Cohesin (SMC1A, SMC1B, SMC3) · Condensin (NCAPD2, NCAPD3, NCAPG, NCAPG2, NCAPH, NCAPH2, SMC2, SMC4) · DNA repair (SMC5, SMC6)
Transition nuclear protein: TNP1, TNP2
Nuclear matrix · Nucleoplasm · Nucleoskeleton · Nucleosol
see also transcription factors and intracellular receptorssee also nucleus diseases
B strc: edmb (perx), skel (ctrs), epit, cili, mito, nucl (chro)Categories:- Human proteins
- Chromosome 7 gene stubs
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