Systematic (IUPAC) name
2-phenylquinoline-4-carboxylic acid
Clinical data
AHFS/ International Drug Names
Pregnancy cat.  ?
Legal status  ?
CAS number 132-60-5
ATC code M04AC02
PubChem CID 8593
ChemSpider 8274 YesY
UNII 39Y533Z02M YesY
KEGG D07280 YesY
Chemical data
Formula C16H11NO2 
Mol. mass 249.264 g/mol
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

Cinchophen (trade names Atophan, Quinophan, and Phenaquin) is an analgesic drug that was introduced in 1910 and frequently used to treat gout. This drug is still used, in combination with Prednisolone, by veterinarians to treat arthritis in animals.

Use of this drug in humans ceased in the 1930s due to the discovery that cinchophen can cause serious liver damage.[1]

There is some evidence that it stimulates C-Fos.[2]


  1. ^ Cutrín Prieto C, Nieto Pol E, Batalla Eiras A, Casal Iglesias L, Pérez Becerra E, Lorenzo Zúñiga V (1991). "[Toxic hepatitis from cinchophen: report of 3 cases]" (in Spanish; Castilian). Medicina clínica 97 (3): 104–6. PMID 1679861. 
  2. ^ Takayama K, Xiong Y, Miura M (May 1994). "Neuronal expression of Fos protein in the paraventricular nucleus of the hypothalamus after i.p. injection of ulcergenic cinchophen". Neurosci. Lett. 172 (1–2): 55–8. doi:10.1016/0304-3940(94)90661-0. PMID 7916144.