Febuxostat

Drugbox
IUPAC_name = 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-
1,3-thiazole-5-carboxylic acid

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CAS_number = 144060-53-7
CAS_supplemental =
ATC_prefix = M04
ATC_suffix = AA03
ATC_supplemental =
PubChem = 134018
DrugBank =
chemical_formula =
C=16 | H=16 | N=2 | Na= | O=3 | S=1
molecular_weight = 316.374 g/mol
bioavailability =
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pregnancy_US =
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licence_EU = Adenuric

Febuxostat (INN; brand name Adenuric) is an inhibitor of xanthine oxidase for the treatment for gout. [cite journal |author=Stamp LK, O'Donnell JL, Chapman PT |title=Emerging therapies in the long-term management of hyperuricaemia and gout |journal=Internal medicine journal |volume=37 |issue=4 |pages=258–66 |year=2007 |pmid=17388867 |doi=10.1111/j.1445-5994.2007.01315.x]

It was approved by the European Medicines Agency on April 21, 2008. [cite web |url=http://www.ipsen.com/articles/mediacentre/pressreleases/20080505___autorisation_adenuric_eu_10.pdf |title=Adenuric® (febuxostat) receives marketing authorisation in the European Union |accessdate=2008-05-28 |author= |date= |work= |publisher=| accessdate=2008-05-28]

References

External links

* [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16339094&query_hl=1&itool=pubmed_docsum comparaison Febuxostat and Allopurinol]