Uricosuric

Uricosuric

Uricosuric medications (drugs) are substances that increase the excretion of uric acid in the urine, thus reducing uric acid concentrations in plasma. Generally, this effect is achieved by action on the proximal tubule.

Uricosurics often are used in the treatment of gout, a disease in which uric acid crystals deposit in joints and cause pain. By decreasing plasma uric acid levels, these drugs decrease the deposition of crystals in joints, eventually decreasing inflammation and thereby mitigating the pain of gout.

Examples of uricosuric drugs include probenecid, benzbromarone and sulfinpyrazone.

Guaifenesin has uricosuric properties, though its main use is as an expectorant. Losartan also has uricosuric properties, though that is not its main use.

All diuretics raise uric acid levels and are therefore "anti"-uricosurics.

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Look at other dictionaries:

  • uricosuric — [yoor΄i kō syoor′ik] adj. 〚 URICO + s + URIC〛 increasing or promoting the urinary excretion of uric acid * * * u·ri·co·sur·ic (yo͝or ĭ kə so͝orʹĭk) adj. Promoting the excretion of uric acid in the urine.   [From uric …   Universalium

  • uricosuric — [yoor΄i kō syoor′ik] adj. [ URICO + s + URIC] increasing or promoting the urinary excretion of uric acid …   English World dictionary

  • uricosuric — Tending to increase the excretion of uric acid. * * * uri·co·su·ric su̇r ik, shu̇r adj relating to or promoting uricosuria <uricosuric drugs> uricosuric n a uricosuric agent (as probenecid) * * * uri·co·su·ric (u″rĭ ko suґrik) 1 …   Medical dictionary

  • uricosuric drug — a drug, such as probenecid or sulfinpyrazone, that increases the amount of uric acid excreted in the urine. Uricosuric drugs are used to treat gout and other conditions in which the levels of uric acid in the blood are increased, as during… …   Medical dictionary

  • uricosuric — adjective Etymology: irregular from uric Date: circa 1947 relating to or promoting the excretion of uric acid in the urine …   New Collegiate Dictionary

  • uricosuric — adjective Pertaining to gout suppressants that act directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma …   Wiktionary

  • uricosuric — uri·co·su·ric …   English syllables

  • uricosuric — adjective acting to increase the excretion of uric acid in the urine • Pertains to noun: ↑urine …   Useful english dictionary

  • uricosuric drug — a drug, such as probenecid or sulfinpyrazone, that increases the amount of uric acid excreted in the urine …   The new mediacal dictionary

  • Средство Уриколитическое (Uricosuric Drug) — лекарственное вещество (такое, например, как пробенецид или сульфинпиразон), способствующее выведению из организма мочевой кислоты. Эти вещества применяются для лечения подагры и некоторых других заболеваний, сопровождающихся повышением… …   Медицинские термины

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