Osler's node

Osler's lesions found on the hand and fingers of a 43 year old male with subacute bacterial endocarditis.

Osler's nodes are painful, red, raised lesions found on the hands and feet. They are associated with a number of conditions, including infective endocarditis, and are caused by immune complex deposition. They are named after Sir William Osler who described them in the early 20th century.^[1][2] Their presence is one definition of Osler's sign.^[3]

Causes

Osler's nodes result from the deposition of immune complexes.^{[citation needed]} The resulting inflammatory response leads to swelling, redness, and pain that characterize these lesions.

The nodes are commonly indicative of subacute bacterial endocarditis.^[4] 10–25% of endocarditis patients will have Osler's nodes.^{[citation needed]} Other signs of endocarditis include Roth's spots and Janeway lesions. The latter, which also occur on the palms and soles, can be differentiated from Osler's nodes because they are nontender.^[5]

It can also be seen in

• systemic lupus erythematosus
• marantic endocarditis
• disseminated gonococcal infection
• distal to infected arterial catheter

External links

• Picture of Osler's nodes and Janeway's lesions

References

1. ^ synd/1702 at Who Named It?
2. ^ W. Osler. Chronic infectious endocarditis. Quarterly Journal of Medicine, Oxford, 1908-1909, 2: 219-230.
3. ^ "Osler sign" at Dorland's Medical Dictionary
4. ^ "Osler nodes" at Dorland's Medical Dictionary
5. ^ Farrior JB, Silverman ME (August 1976). "A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis". Chest 70 (2): 239–43. doi:10.1378/chest.70.2.239. PMID 947688. http://www.chestjournal.org/cgi/pmidlookup?view=long&pmid=947688. 

This medical sign article is a stub. You can help Wikipedia by expanding it.v · Categories: Medical sign stubs Symptoms and signs: Cardiac Wikimedia Foundation. 2010. Игры ⚽ Нужно сделать НИР? Grayson Hall Orbit attitude and maneuvering system Look at other dictionaries: Osler's sign — refers to one of the medical signs named in honor of the famous Professor William Osler, Professor of Medicine at McGill University and Johns Hopkins University. Osler s sign (pseudohypertension) Pretibial myxedema seen in Graves disease is also… …   Wikipedia Node — Literally a knot, a node is a collection of tissue. For example a lymph node, is a collection of lymphoid tissue. A nodule is a small node, a little collection of tissue. * * * 1. A knob or nodosity; a circumscribed swelling; in anatomy, a… …   Medical dictionary Osler node — noun A painful, red, raised skin lesion, usually on the pads of the fingers or toes, indicative of the heart disease bacterial endocarditis. The patient had fever and sweats for weeks, but the diagnosis was uncertain until Osler nodes appeared on …   Wiktionary Osler disease maneuver nodes etc. — Os·ler disease, maneuver, nodes, etc. (ōsґlər) [Sir William Osler, Canadian born physician, 1849–1919; successively professor of medicine in McGill University, the University of Pennsylvania, Johns Hopkins University, and the… …   Medical dictionary Osler — Sir William, Canadian physician in U.S. and England, 1849–1919. See O. disease, O. node, O. sign, Rendu O. Weber syndrome. * * * objectively structured long examination record …   Medical dictionary Janeway lesion — Janeway lesions are non tender, small erythematous or haemorrhagic macular or nodular lesions on the palms or soles only a few millimeters in diameter that are pathognomonic of infective endocarditis.cite journal | last = Farrior | first = J.B. | …   Wikipedia Endocarditis — eMedicine2|ped|2511 MeshID = D004696 Endocarditis is an inflammation of the inner layer of the heart, the endocardium. It usually involves the heart valves (native or prosthetic valves). Other structures which may be involved include the… …   Wikipedia Heart murmur — For the French motion picture, see Murmur of the Heart. Cardiac murmurs and other cardiac sounds Auscultogram from normal and abnormal heart sounds ICD 10 …   Wikipedia Watson's water hammer pulse — is the medical sign which describes a pulse that is bounding and forceful,[1] or, in other words, rapidly increasing and subsequently collapsing,[2] as if it were the hitting of a water hammer that was causing the pulse. This is associated with… …   Wikipedia Osborn wave — Schematic representation of normal ECG Atrial fibrillation …   Wikipedia 18+ © Academic, 2000-2025 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”