- Aschoff body
Aschoff bodies or Aschoff nodules are painless nodules present in
rheumatic fever .Appearance
It is an area of focal interstitial myocardial inflammation. Fully developed Aschoff bodies consist of fibrinoid change in
connective tissue ,lymphocyte s, occasionalplasma cell s, and abnormal characteristichistiocyte s. They are Aschoff cellgranulomas with a fibrinoid necrotic centre found in themyocardium surroundingblood vessel s, and other regions of the body.Myocyte s in the myocardium can merge with the Aschoff cells to form giant cells of Aschoff, In addition, there areleukocytes ,lymphocytes ,eosinophils andplasma cells andAnitschkow myocyte s.History
The Aschoff bodies were discovered independently by the German pathologist
Ludwig Aschoff 1904 and one year later byPaul Rudolf Geipel . [WhoNamedIt|synd|231] [K. A. L. Aschoff. Zur Myocarditisfrage. Verhandlungen der deutschen pathologischen Gesellschaft, Stuttgart, 1904, 8: 46-53. Translated in Willius & Keys, Cardiac Classics, 1941, pp. 733-739.]References
External links
* http://erl.pathology.iupui.edu/C603/GENE426.HTM
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