MVA85A

MVA85A (modified vaccinia Ankara 85A) is a new-generation vaccine against tuberculosis developed by researchers at Oxford University. This vaccine produces higher levels of long-lasting cellular immunity when used together with the old TB vaccine called BCG.^[1] Phase I clinical trials have been completed^[2] and phase II clinical trials are currently underway in South Africa.^[3]

External links

• New TB vaccine shown to be safe

References

1. ^ McShane H, Pathan AA, Sander CR, et al. (2004). "Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG primed and naturally acquired anti-microbial immunity in humans". Nat Med 10 (11): 1240–44. doi:10.1038/nm1128. PMID 15502839. 
2. ^ Hawkridge T, Scriba TJ, Gelderbloem, et al. (2008). "Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa". J Infect Dis 198 (4): 544–52. doi:10.1086/590185. PMC 2822902. PMID 18582195. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2822902. 
3. ^ Ibanga H, Brookes R, Hill P, Owiafe P, Fletcher H, Lienhardt C, Hill A, Adegbola R, McShane H (2006). "Early clinical trials with a new tuberculosis vaccine, MVA85A, in tuberculosis-endemic countries: issues in study design". Lancet Infect Dis 6 (8): 522–8. doi:10.1016/S1473-3099(06)70552-7. PMID 16870530. 

This vaccine article is a stub. You can help Wikipedia by expanding it.v · Categories: Tuberculosis Vaccines Vaccine stubs Wikimedia Foundation. 2010. Игры ⚽ Нужна курсовая? Dimercaprol Americanism (heresy) Look at other dictionaries: Tuberculosis — Classification and external resources Chest X ray of a person with advanced tuberculosis ICD 10 A …   Wikipedia Mantoux test — The Mantoux skin test consists of an intradermal injection of exactly one tenth of a milliliter (mL) of PPD tuberculin …   Wikipedia Chest photofluorography — Chest radiography showing advanced bilateral pulmonary tuberculosis. Source: CDC Chest photofluorography, or abreugraphy (also called mass miniature radiography) is a photofluorography technique for mass screening for tuberculosis using a… …   Wikipedia Tuberculosis vaccines — are vaccinations intended for the prevention of tuberculosis. There is currently only one tuberculosis vaccine available, bacille Calmette Guérin (BCG).Other tuberculosis vaccines currently in development are: * MVA85A * rBCG30 * 72F fusion… …   Wikipedia Mycobacterium caprae — Scientific classification Kingdom: Bacteria Phylum: Actinobacteria Order …   Wikipedia Multi-drug-resistant tuberculosis — Classification and external resources MeSH D018088 Multi drug resistant tuberculosis (MDR TB) is defined as TB that is resistant at least to isoniazid (INH) and rifampicin (RMP), the two most powerful …   Wikipedia Microscopic Observation Drug Susceptibility assay — The Microscopic Observation Drug Susceptibility assay (MODS) is a culture method shown to be more sensitive, faster and cheaper test than current culture based tests for Tuberculosis. The Microscopic Observation Drug Susceptibility assay (MODS)… …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”