- Desmosine
-
Desmosine 4-(4-amino-4-carboxybutyl)-1-(5-amino-5-carboxypentyl)-3,5-bis(3-amino-3-carboxypropyl)pyridiniumIdentifiers CAS number 11003-57-9 PubChem 25435 ChemSpider 23745 Jmol-3D images Image 1 - O=C(O)C(N)CCCC[n+]1cc(c(c(c1)CCC(C(=O)O)N)CCCC(C(=O)O)N)CCC(C(=O)O)N
- InChI=1S/C24H39N5O8/c25-17(21(30)31)5-1-2-11-29-12-14(7-9-19(27)23(34)35)16(4-3-6-18(26)22(32)33)15(13-29)8-10-20(28)24(36)37/h12-13,17-20H,1-11,25-28H2,(H3-,30,31,32,33,34,35,36,37)/p+1
Key: VEVRNHHLCPGNDU-UHFFFAOYSA-O
InChI=1/C24H39N5O8/c25-17(21(30)31)5-1-2-11-29-12-14(7-9-19(27)23(34)35)16(4-3-6-18(26)22(32)33)15(13-29)8-10-20(28)24(36)37/h12-13,17-20H,1-11,25-28H2,(H3-,30,31,32,33,34,35,36,37)/p+1
Key: VEVRNHHLCPGNDU-IKLDFBCSAT
Properties Molecular formula C24H40N5O8 Molar mass 526.6 g mol−1 (verify) (what is: / ?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)Infobox references A desmosine cross-link is formed from three allysyl side chains plus one unaltered lysyl side chain from the same or neighbouring polypeptides.
It is found in elastin. Desmosine causes a yellow color.
This desmosine is responsible for the rubber properties of elastin.
Protein primary structure and posttranslational modifications General N terminus C terminus Single specific AAs Phosphorylation · Sulfation · Porphyrin ring linkage · Adenylylation · Flavin linkage · Topaquinone (TPQ) formationAspartateGlutamateTransglutaminationMethylation · Acetylation · Acylation · Adenylylation · Hydroxylation · Ubiquitination · Sumoylation · ADP-ribosylation · Deamination · Oxidative deamination to aldehyde · O-glycosylation · Imine formation · Glycation · CarbamylationDiphthamide formation · AdenylylationCrosslinks between two AAs Sulfilimine bondLysine-TyrosylquinoneLysine tyrosylquinone (LTQ) formationTryptophan-TryptophylquinoneThree consecutive AAs
(Chromophore formation)4-(p-hydroxybenzylidene)-5-imidazolinone formationCrosslinks between four AAs DesmosineSecondary structure→This protein-related article is a stub. You can help Wikipedia by expanding it.