Methisazone

Methisazone
Methisazone
Identifiers
CAS number 1910-68-5 YesY
PubChem 6861563
UNII K3QML4J07E N
ChEMBL CHEMBL1512080 N
Jmol-3D images Image 1
Properties
Molecular formula C10H10N4OS
Molar mass 234.28 g/mol
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Methisazone is an antiviral drug that works by inhibiting mRNA and protein synthesis, especially in pox viruses. It has been used in the past to treat smallpox.[1]

Methisazone has been described as being used in prophylaxis since at least 1965.[2][3]

References

  1. ^ Methisazone, Merriam-Webster's Medical Dictionary
  2. ^ do Valle, LA; de Melo, PR; de Gomes, LF; Proença, LM (13 Nov 1965). "Methisazone in prevention of variola minor among contacts". Lancet 2 (7420): 976–8. PMID 4159212. 
  3. ^ Weiss MM, Weiss PD, Mathisen G, Guze P (December 2004). "Rethinking smallpox". Clin. Infect. Dis. 39 (11): 1668–73. doi:10.1086/425745. PMID 15578369. http://www.journals.uchicago.edu/cgi-bin/resolve?CID34015.