Orotidine 5'-monophosphate

Orotidine 5'-monophosphate: Orotidine 5'-monophosphate

IUPAC name

3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]-2,6-dioxo-pyrimidine-4-carboxylic acid

Other names

Orotidylic acid,
OMP

Identifiers

CAS number 2149-82-8

PubChem 968

MeSH Orotidine+5'-monophosphate

Jmol-3D images Image 1

SMILES

C1=C(N(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O)C(=O)O

Properties

Molecular formula C₁₀H₁₃N₂O₁₁P

Molar mass 368.191 g/mol

Y 5'-monophosphate (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

Infobox references

Orotidine 5'-monophosphate (OMP), also known as orotidylic acid, is a pyrimidine nucleotide which is the last intermediate in the biosynthesis of uridine monophosphate. OMP is formed from orotate and phosphoribosyl pyrophosphate by the enzyme Orotate phosphoribosyltransferase

In humans, the enzyme UMP synthase converts OMP into uridine 5'- monophosphate. If UMP synthase is defective, orotic aciduria can result.

v · d · eNucleotide metabolic intermediates

Purine metabolism

Anabolism

R5P→IMP: R5P · PRPP · PRA · GAR · FGAR · FGAM · AIR · CAIR · SAICAR · AICAR · FAICAR

IMP→AMP: Adenylosuccinate
IMP→GMP: Xanthosine monophosphate

Catabolism

Hypoxanthine · Xanthine · Uric acid · 5-Hydroxyisourate

Pyrimidine metabolism

Anabolism

Carbamoyl phosphate · Carbamoyl aspartic acid · 4,5-Dihydroorotic acid · Orotic acid · Orotidine 5'-monophosphate · Uridine monophosphate

Catabolism

uracil: Dihydrouracil · 3-Ureidopropionic acid · β-Alanine
thymine: Dihydrothymine · β-Ureidoisobutyric acid · 3-Aminoisobutyric acid

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)

biochemical families: prot · nucl · carb (glpr, alco, glys) · lipd (fata/i, phld, strd, gllp, eico) · amac/i · ncbs/i · ttpy/i

Categories:
Nucleotides
Pyrimidinediones
Biochemistry stubs

Orotidine 5'-monophosphate

IUPAC name 3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]-2,6-dioxo-pyrimidine-4-carboxylic acid
Other names Orotidylic acid, OMP
Identifiers
CAS number	2149-82-8
PubChem	968
MeSH	Orotidine+5'-monophosphate
Jmol-3D images	Image 1
SMILES C1=C(N(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O)C(=O)O
Properties
Molecular formula	C₁₀H₁₃N₂O₁₁P
Molar mass	368.191 g/mol
Y 5'-monophosphate (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

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Look at other dictionaries:

orotidine-5ˊ-monophosphate — orotidin 5ˊ monofosfatas statusas T sritis chemija apibrėžtis Nukleotidas. santrumpa( os) OMP atitikmenys: angl. orotidine 5ˊ monophosphate rus. оротидин 5ˊ монофосфат … Chemijos terminų aiškinamasis žodynas
Orotidine 5'-phosphate decarboxylase — E. coli OMP decarboxylase.[1] Identifiers EC number … Wikipedia
orotidine — Orotic acid 3 β d ribonucleoside; uridine 6 carboxylic acid; elevated in cases of orotidinuria. SYN: 1 ribosylorotate. o. 5′ monophosphate (OMP) SYN: orotidylic acid. * * * orot·i·dine (ə rotґĭ dēn) a nucleoside, orotic acid linked … Medical dictionary
orotidine-5‵ — phosphate decarboxylase (ODC) orot·i·dine 5‵ phos·phate de·car·box·y·lase (ODC) (ə rotґĭ dēn fosґfāt de″kahr bokґsə lās) [EC 4.1.1.23] an enzyme of the lyase class that catalyzes the decarboxylation of… … Medical dictionary

Uridine monophosphate synthetase — PDB rendering based on 2eaw … Wikipedia

Uridine monophosphate — Chembox new ImageFile=UMP chemical structure.png ImageSize= IUPACName= OtherNames= Section1= Chembox Identifiers CASNo=58 97 9 PubChem=1172 SMILES=C1=CN(C(=O)NC1=O) C2C(C(C(O2)COP(=O)(O)O)O)O MeSHName=Uridine+monophosphate Section2= Chembox… … Wikipedia

orotidylic acid — Orotidine 5′ monophosphate; an intermediate in the biosynthesis of the pyrimidine nucleosides (cytidine and uridine) that are found in nucleic acid s. SYN: orotidine 5′ monophosphate. o. decarboxylase an enzyme that catalyzes the conversion of… … Medical dictionary

OMP — Abbreviation for oligo N methylmorpholinium propylene oxide; orotidylic acid; orotidylate; orotidine 5′ monophosphate. * * * olfactory marker protein; oligonucleoside methylphosphonate; ornithine monophosphate; orotidine 5´ monophos phatase;… … Medical dictionary

uridylic acid — Uridine esterified by phosphoric acid on one or more sugar hydroxyl groups; UMP is typically uridine 5′ monophosphate; 2′ and 3′ derivatives also occur; precursor for the biosynthesis of other pyrimidine nucleotides. SYN: UMP synthase, uridine 5′ … Medical dictionary

Xanthine — Not to be confused with xanthene. Xanthine … Wikipedia

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Orotidine 5'-monophosphate

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