Orotidine 5'-monophosphate

Orotidine 5'-monophosphate
Orotidine 5'-monophosphate
Identifiers
CAS number 2149-82-8
PubChem 968
MeSH Orotidine+5'-monophosphate
Jmol-3D images Image 1
Properties
Molecular formula C10H13N2O11P
Molar mass 368.191 g/mol
 YesY 5'-monophosphate (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Orotidine 5'-monophosphate (OMP), also known as orotidylic acid, is a pyrimidine nucleotide which is the last intermediate in the biosynthesis of uridine monophosphate. OMP is formed from orotate and phosphoribosyl pyrophosphate by the enzyme Orotate phosphoribosyltransferase

In humans, the enzyme UMP synthase converts OMP into uridine 5'- monophosphate. If UMP synthase is defective, orotic aciduria can result.



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  • orotidine-5ˊ-monophosphate — orotidin 5ˊ monofosfatas statusas T sritis chemija apibrėžtis Nukleotidas. santrumpa( os) OMP atitikmenys: angl. orotidine 5ˊ monophosphate rus. оротидин 5ˊ монофосфат …   Chemijos terminų aiškinamasis žodynas

  • Orotidine 5'-phosphate decarboxylase — E. coli OMP decarboxylase.[1] Identifiers EC number …   Wikipedia

  • orotidine — Orotic acid 3 β d ribonucleoside; uridine 6 carboxylic acid; elevated in cases of orotidinuria. SYN: 1 ribosylorotate. o. 5′ monophosphate (OMP) SYN: orotidylic acid. * * * orot·i·dine (ə rotґĭ dēn) a nucleoside, orotic acid linked …   Medical dictionary

  • orotidine-5 — phosphate decarboxylase (ODC) orot·i·dine 5‵ phos·phate de·car·box·y·lase (ODC) (ə rotґĭ dēn fosґfāt de″kahr bokґsə lās) [EC 4.1.1.23] an enzyme of the lyase class that catalyzes the decarboxylation of… …   Medical dictionary

  • Uridine monophosphate synthetase — PDB rendering based on 2eaw …   Wikipedia

  • Uridine monophosphate — Chembox new ImageFile=UMP chemical structure.png ImageSize= IUPACName= OtherNames= Section1= Chembox Identifiers CASNo=58 97 9 PubChem=1172 SMILES=C1=CN(C(=O)NC1=O) C2C(C(C(O2)COP(=O)(O)O)O)O MeSHName=Uridine+monophosphate Section2= Chembox… …   Wikipedia

  • orotidylic acid — Orotidine 5′ monophosphate; an intermediate in the biosynthesis of the pyrimidine nucleosides (cytidine and uridine) that are found in nucleic acid s. SYN: orotidine 5′ monophosphate. o. decarboxylase an enzyme that catalyzes the conversion of… …   Medical dictionary

  • OMP — Abbreviation for oligo N methylmorpholinium propylene oxide; orotidylic acid; orotidylate; orotidine 5′ monophosphate. * * * olfactory marker protein; oligonucleoside methylphosphonate; ornithine monophosphate; orotidine 5´ monophos phatase;… …   Medical dictionary

  • uridylic acid — Uridine esterified by phosphoric acid on one or more sugar hydroxyl groups; UMP is typically uridine 5′ monophosphate; 2′ and 3′ derivatives also occur; precursor for the biosynthesis of other pyrimidine nucleotides. SYN: UMP synthase, uridine 5′ …   Medical dictionary

  • Xanthine — Not to be confused with xanthene. Xanthine …   Wikipedia

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