- Orotidine 5'-monophosphate
Orotidine 5'-monophosphate3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]-2,6-dioxo-pyrimidine-4-carboxylic acidOther namesOrotidylic acid,
Identifiers CAS number 2149-82-8 PubChem 968 MeSH Orotidine+5'-monophosphate Jmol-3D images Image 1
Properties Molecular formula C10H13N2O11P Molar mass 368.191 g/mol 5'-monophosphate (verify) (what is: /?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Orotidine 5'-monophosphate (OMP), also known as orotidylic acid, is a pyrimidine nucleotide which is the last intermediate in the biosynthesis of uridine monophosphate. OMP is formed from orotate and phosphoribosyl pyrophosphate by the enzyme Orotate phosphoribosyltransferase
In humans, the enzyme UMP synthase converts OMP into uridine 5'- monophosphate. If UMP synthase is defective, orotic aciduria can result.
Nucleotide metabolic intermediates Purine metabolismAnabolismCatabolism Pyrimidine metabolismAnabolismCarbamoyl phosphate · Carbamoyl aspartic acid · 4,5-Dihydroorotic acid · Orotic acid · Orotidine 5'-monophosphate · Uridine monophosphateCatabolismbiochemical families: prot · nucl · carb (glpr, alco, glys) · lipd (fata/i, phld, strd, gllp, eico) · amac/i · ncbs/i · ttpy/iCategories:
- Biochemistry stubs
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