Xanthosine monophosphate

Xanthosine monophosphate

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Section1= Chembox Identifiers
CASNo=523-98-8
PubChem=122280
SMILES=
MeSHName=Xanthosine+monophosphate
Section2= Chembox Properties
Formula=C10H13N4O9P
MolarMass=364.206 g/mol
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Section3= Chembox Hazards
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Xanthosine monophosphate is an intermediate in purine metabolism, formed from IMP, and forming GMP.

Clinical significance

Xanthylic acid can be used in quantitative measurements of the inosine monophosphate dehydrogenase enzyme activities in purine metabolism, as recommended to ensure optimal thiopurine therapy for children with acute lymphoblastic leukaemia (ALL).cite journal |author=Khalil PN, Erb N, Khalil MN, Escherich G, Janka-Schaub GE |title=Validation and application of a high-performance liquid chromatographic-based assay for determination of the inosine 5'-monophosphate dehydrogenase activity in erythrocytes |journal=J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |volume=842 |issue=1 |pages=1–7 |year=2006 |month=September |pmid=16725387 |doi=10.1016/j.jchromb.2006.04.040 |url=http://linkinghub.elsevier.com/retrieve/pii/S1570-0232(06)00373-4]

References


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