- Normal anion gap acidosis
Normal anion gap acidosis Classification and external resources ICD-10 E87.2 ICD-9 276.2 DiseasesDB 29144
In renal physiology, normal anion gap acidosis, and less precisely non-anion gap acidosis, is an acidosis that is not accompanied by an abnormally increased anion gap.
The most common etiology of normal anion gap acidosis is diarrhea with a renal tubular acidosis being a distant second .
The differential diagnosis of normal anion gap acidosis is relatively short (when compared to the differential diagnosis of acidosis):
- Acetazolamide and other carbonic anhydrase inhibitors
- Renal tubular acidosis
- Ureteroenteric fistula - an abnormal connection (fistula) between a ureter and the gastrointestinal tract
- Pancreaticoduodenal fistula - an abnormal connection between the pancreas and duodenum
It can be remembered with the mnemonic HARD-UP.
As opposed to high anion gap acidosis (which involves increased organic acid production), normal anion gap acidosis involves either increased production of chloride (hyperchloremic acidosis) or increased excretion of bicarbonate.
- ^ "Metabolic Acidosis: Acid-Base Regulation and Disorders: Merck Manual Professional". http://www.merck.com/mmpe/sec12/ch157/ch157c.html#sec12-ch157-ch157c-1035. Retrieved 2008-12-04.
- ^ Mnemonic at medicalmnemonics.com 1797
Water-electrolyte imbalance and acid-base imbalance (E86–E87, 276) Volume statusVolume contraction (Dehydration/Hypovolemia) · Hypervolemia ElectrolyteHypernatremia · Hyponatremia (Hypotonic, Isotonic) Acid-baseMetabolic: High anion gap (Ketoacidosis/Diabetic ketoacidosis, Lactic) · Normal anion gap (Hyperchloremic, Renal tubular)BothCategories:
- Medicine stubs
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