Hyperchloremic acidosis

Hyperchloremic acidosis

DiseaseDisorder infobox
Name = Hyperchloremic acidosis
ICD10 = ICD10|E|87|2|e|70
ICD9 = ICD9|276.2


Caption =
ICDO =
OMIM =
DiseasesDB =
MedlinePlus =
eMedicineSubj = med
eMedicineTopic = 1071

Hyperchloremic acidosis is a form of metabolic acidosis associated with a normal anion gap, a decrease in plasma bicarbonate concentration, and in an increase in plasma chloride concentration (see anion gap for a fuller explanation).

Causes

*Renal tubular acidosis failure of HCO3- resorption("i.e.", proximal renal tubular acidosis) or failure of H+ secretion (ie in distal renal tubular acidosis)
*Renal failure
*Gastrointestinal loss of HCO3- with diarrhea (vomiting will tend to cause hypochloraemic alkalosis).
*Ingestions
**Ammonium chloride, Hydrochloric acid
**Hyperalimentation fluids ("i.e.", total parenteral nutrition)

* Alcohol (such as ethanol) can effect anion gap by inducing alcohol dehydrogenase enzyme.

ee also

*Anion gap
*Metabolic acidosis

External links

*
* [http://kidney.niddk.nih.gov/kudiseases/pubs/tubularacidosis/ NIH - Renal Tubular Acidosis]


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