Chemical modification

In biochemistry, chemical modification is the technique of chemically reacting a protein or nucleic acid with chemical reagents. Chemical modification can have several goals, such as

• to identify which parts of the molecule are exposed to solvent ("foot printing");
• to determine which residues are important for a particular phenotype, e.g., which residues are important for an enzymatic activity;
• to introduce new groups into a macromolecule; and
• to crosslink macromolecules intra- and intermolecularly.

Chemical modification of protein side chains

• Iodoacetamide
• Iodoacetic acid
• PEGylation
• BisSulfosuccinimidyl suberate
• 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide
• N-Ethylmaleimide
• Methyl methanethiosulfonate (MMTS)
• MTSL

Chemical modification of nucleic acids

This protein-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Protein structure Protein stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем сделать НИР Gottfredo Baur List of television and radio stations in Iloilo City Look at other dictionaries: chemical modification — cheminis modifikavimas statusas T sritis chemija apibrėžtis Cheminės reakcijos, kurių metu keičiama medžiagos sudėtis ir savybės. atitikmenys: angl. chemical modification; modification rus. модификация; химическая модификация ryšiai: sinonimas –… …   Chemijos terminų aiškinamasis žodynas Chemical force microscopy — Figure 1: Photograph of an AFM system which can be used for chemical force microscopy. Chemical force microscopy (CFM) is a variation of atomic force microscopy (AFM) which has become a versatile tool for characterization of materials surfaces.… …   Wikipedia modification — cheminis modifikavimas statusas T sritis chemija apibrėžtis Cheminės reakcijos, kurių metu keičiama medžiagos sudėtis ir savybės. atitikmenys: angl. chemical modification; modification rus. модификация; химическая модификация ryšiai: sinonimas –… …   Chemijos terminų aiškinamasis žodynas Chemical biology — is a scientific discipline spanning the fields of chemistry and biology that involves the application of chemical techniques and tools, often compounds produced through synthetic chemistry, to the study and manipulation of biological systems.… …   Wikipedia Chemical King — Publication information Publisher DC Comics First appearance …   Wikipedia Chemical castration — is the administration of medication designed to reduce libido and sexual activity, usually in the hope of preventing rapists, child molesters and other sex offenders from repeating their crimes. Unlike surgical castration, where the testicles or… …   Wikipedia chemical bonding — ▪ chemistry Introduction       any of the interactions that account for the association of atoms into molecules, ions, crystals, and other stable species that make up the familiar substances of the everyday world. When atoms approach one another …   Universalium Chemical vapor deposition — DC plasma (violet) enhances the growth of carbon nanotubes in this laboratory scale PECVD apparatus. Chemical vapor deposition (CVD) is a chemical process used to produce high purity, high performance solid materials. The process is often used in …   Wikipedia Modification post-transcriptionnelle — Les modifications post transcriptionnelles représentent l ensemble les modifications qu un ARN subit après avoir été transcrit. On parle également de maturation de l’ARN. Les modifications les plus connues sont l ajout d une coiffe, la… …   Wikipédia en Français Chemical kinetics — Reaction rate tends to increase with concentration a phenomenon explained by collision theory. Chemical kinetics, also known as reaction kinetics, is the study of rates of chemical processes. Chemical kinetics includes investigations of how… …   Wikipedia 18+ © Academic, 2000-2025 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”