- NLRP9
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NLR family, pyrin domain containing 9 Identifiers Symbols NLRP9; CLR19.1; NALP9; NOD6; PAN12 External IDs OMIM: 609663 MGI: 2675377 HomoloGene: 18530 GeneCards: NLRP9 Gene Gene Ontology Molecular function • nucleotide binding
• ATP bindingCellular component • cytoplasm Biological process • translation
• proteolysisSources: Amigo / QuickGO Orthologs Species Human Mouse Entrez 338321 243874 Ensembl ENSG00000185792 ENSMUSG00000060508 UniProt Q7RTR0 Q66X22 RefSeq (mRNA) NM_176820 NM_194058.2 RefSeq (protein) NP_789790 NP_918947.2 Location (UCSC) Chr 19:
56.22 – 56.25 MbChr 7:
20.59 – 20.66 MbPubMed search [1] [2] NLRP9, short for NOD-like receptor family pyrin domain containing 9, is an intracellular protein that is expressed in the ovaries, testes, oocytes, and preimplantation embryos of mammals that is likely involved in reproductive processes.[1][2][3] It is also known as NALP9, NOD6, PAN12, and CLR19.1, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.
References
- ^ Dalbiès-Tran R, Papillier P, Pennetier S, Uzbekova S, Monget P (August 2005). "Bovine mater-like NALP9 is an oocyte marker gene". Mol. Reprod. Dev. 71 (4): 414–21. doi:10.1002/mrd.20298. PMID 15892040.
- ^ Ponsuksili S, Brunner RM, Goldammer T, et al. (March 2006). "Bovine NALP5, NALP8, and NALP9 genes: assignment to a QTL region and the expression in adult tissues, oocytes, and preimplantation embryos". Biol. Reprod. 74 (3): 577–84. doi:10.1095/biolreprod.105.045096. PMID 16339045.
- ^ Tian X, Pascal G, Monget P (2009). "Evolution and functional divergence of NLRP genes in mammalian reproductive systems". BMC Evol. Biol. 9: 202. doi:10.1186/1471-2148-9-202. PMC 2735741. PMID 19682372. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2735741.
Further reading
- Inohara N, Nuñez G (2003). "NODs: intracellular proteins involved in inflammation and apoptosis.". Nat. Rev. Immunol. 3 (5): 371–82. doi:10.1038/nri1086. PMID 12766759.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Tschopp J, Martinon F, Burns K (2003). "NALPs: a novel protein family involved in inflammation.". Nat. Rev. Mol. Cell Biol. 4 (2): 95–104. doi:10.1038/nrm1019. PMID 12563287.
CARD domain containing Pyrin domain containing Apoptosis inhibitory protein Family member X1 
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