- Corticorelin
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Corticorelin Clinical data AHFS/Drugs.com International Drug Names Pregnancy cat. ? Legal status ? Identifiers CAS number 79804-71-0 ATC code V04CD04 PubChem CID 16132344 UNII 305OE8862Y Chemical data Formula C205H339N59O63S Mol. mass 4670.31 g/mol (what is this?) (verify)
Corticorelin is a diagnostic agent. It is a corticotropin-releasing hormone.[1]
The corticorelin stimulation test helps to differentiate between the etiologies of ACTH-dependent hypercortisolism. It is used to evaluate the status of the pituitary-adrenal axis in the differentiation of a pituitary source from an ectopic source of excessive ACTH secretion.
- If corticorelin injection increases plasma levels of ACTH and cortisol, a diagnosis of Cushing's disease is achieved (ACTH of pituitary origin).
- If corticorelin injection leads to little or no response in plasma levels of ACTH or cortisol, a diagnosis of Ectopic ACTH syndrome is confirmed.
See also
References
Pituitary functionInulin and other polyfructosans • Indigo carmine • Phenolsulfonphthalein • Alsactide • Aminohippuric acidCategories:- Pharmacology stubs
- Peptides
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