- Mantle zone
-
Germinal centre Image labeled in German, but "Mantel-zone" visible near center. The mantle zone (or just mantle) of a lymphatic nodule (or lymphatic follicle) is an outer ring of small lymphocytes surrounding a germinal center.[1]
It is also known as the "corona".[2]
It contains transient lymphocytes.[3]
It is the location of the lymphoma in mantle cell lymphoma.
Pathology
Mantle zone expansion may be seen in benign, such as Castleman disease, and malignancy, i.e. Mantle cell lymphoma.
References
External links
- http://erl.pathology.iupui.edu/HISTO/LABE109.HTM
- Histology at BU 07102loa - "Lymphoid Tissues and Organs: lymph node, cortex and medulla"
Lymphoid system (TA A13.1–2, TH H3.10, GA 8 and 9) Primary lymphoid organs Secondary lymphoid organs structural: Hilum · Trabeculae · Diaphragmatic surface of spleen · Visceral surface of spleen
Red pulp (Cords of Billroth, Marginal zone)
White pulp (Periarteriolar lymphoid sheaths, Germinal center)
blood flow: Trabecular arteries · Trabecular veinslymph flow: Afferent lymph vessels · Cortical sinuses · Medullary sinuses · Efferent lymph vessels
T cells: High endothelial venules
B cells: Primary follicle/Germinal center · Mantle zone · Marginal zone
layers: Capsule/Trabeculae · Subcapsular sinus · Cortex · Paracortex · Medulla (Medullary cord) · HilumMALT
(process mucosa)M: LMO
anat(h, u, t, a, l)/phys/depv
noco/cong/tumr
proc
Categories:- Lymphatic system stubs
- Lymphatic organ anatomy
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