Meigs syndrome

Meigs syndrome
Classification and external resources
DiseasesDB	7943
eMedicine	med/1422
MeSH	D008539

Not to be confused with Meige syndrome

In medicine, Meigs syndrome, also Meigs' syndrome, is the triad of ascites, pleural effusion and benign ovarian tumor (fibroma).^[1][2] It resolves after the resection of the tumor. For reasons unknown, the pleural effusion is classically on the right side.

Differential diagnosis

It may mimic other conditions.^[3]

Because of the presence of ascites and transudative pleural effusions, the differential diagnosis includes liver failure (cirrhosis), congestive heart failure, renal diseases, and metastatic tumors to the peritoneal surfaces. These entities must be clinically excluded.^{[citation needed]}

Treatment

Treatment of Meigs' syndrome consists of thoracentesis and paracentesis to drain off the excess fluid (transudate), and unilateral salpingo-oophorectomy or wedge resection to correct the underlying etiology.

Eponym

Meigs' Syndrome is named for Joe Vincent Meigs.^[4][5][6]

References

1. ^ Meigs syndrome at eMedicine
2. ^ Morán-Mendoza A, Alvarado-Luna G, Calderillo-Ruiz G, Serrano-Olvera A, López-Graniel CM, Gallardo-Rincón D (2006). "Elevated CA125 level associated with Meigs' syndrome: case report and review of the literature". Int. J. Gynecol. Cancer 16 (Suppl 1): 315–318. doi:10.1111/j.1525-1438.2006.00228.x. PMID 16515612. 
3. ^ Lanitis S, Sivakumar S, Behranwala K, Zacharakis E, Al Mufti R, Hadjiminas DJ (2009). "A case of Meigs syndrome mimicking metastatic breast carcinoma". World J Surg Oncol 7: 10. doi:10.1186/1477-7819-7-10. PMC 2633000. PMID 19161612. http://www.wjso.com/content/7//10. 
4. ^ Meigs' syndrome at Who Named It?
5. ^ Lurie S (2000). "Meigs' syndrome: the history of the eponym". Eur. J. Obstet. Gynecol. Reprod. Biol. 92 (2): 199–204. doi:10.1016/S0301-2115(99)00289-4. PMID 10996681. http://linkinghub.elsevier.com/retrieve/pii/S0301211599002894. 
6. ^ Meigs JV (May 1954). "Fibroma of the ovary with ascites and hydrothorax; Meigs' syndrome". Am. J. Obstet. Gynecol. 67 (5): 962–85. PMID 13148256.