Iohexol Systematic (IUPAC) name 1-N,3-N-bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide Clinical data AHFS/Drugs.com Pregnancy cat. B(US) Legal status ℞ Prescription only Routes Intrathecal, intravascular, oral, intracavital Pharmacokinetic data Protein binding Low Metabolism Nil Half-life Variable Excretion Renal, unchanged Identifiers CAS number ATC code V08 PubChem DrugBank ChemSpider UNII KEGG ChEBI ChEMBL Chemical data Formula C19H26I3N3O9 Mol. mass 821.138 g/mol SMILES & (what is this?)
Iohexol is a contrast agent, sold under the trade name Omnipaque. It is available in various concentrations, from 140 to 350 milligrams of iodine per milliliter. Omnipaque 350 is commonly used as a contrast agent during coronary angiography.
The osmolality of iohexol ranges from 322 mOsm/kg—approximately 1.1 times that of blood plasma—to 844 mOsm/kg, almost three times that of blood. Despite this difference, iohexol is still considered a low-osmolality contrast agent; the osmolality of older agents, such as diatrizoate, may be more than twice as high.
- ^ GE Healthcare (May 2006). "Omnipaque (Iohexol) injection. Product label". DailyMed. U.S. National Library of Medicine. http://dailymed.nlm.nih.gov/dailymed/fdaDrugXsl.cfm?id=3465&type=display. Retrieved 2007-03-28.
- ^ Amersham Health (April 2006). "Hypaque (Diatrizoate Meglumine and Diatrizoate Sodium) injection, solution. Product label". DailyMed. U.S. National Library of Medicine. http://dailymed.nlm.nih.gov/dailymed/fdaDrugXsl.cfm?id=997&type=display. Retrieved 2007-03-29.
Contrast media (V08) X-ray and CTIodinated,
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