Yttrium (90Y) clivatuzumab tetraxetan

Yttrium (90Y) clivatuzumab tetraxetan
Yttrium (90Y) clivatuzumab tetraxetan?
Monoclonal antibody
Type Whole antibody
Source Humanized (from mouse)
Target MUC1
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 943976-23-6 N
ATC code None
Chemical data
Formula C6496H9952N1716O2014S44 
Mol. mass 145.7 kDa
 N(what is this?)  (90Y) clivatuzumab tetraxetan (verify)

Yttrium (90Y) clivatuzumab tetraxetan (trade name hPAM4-Cide) is a humanized monoclonal antibody designed for the treatment of pancreatic cancer.[1] The antibody itself, clivatuzumab, is conjugated with tetraxetan, a chelator for yttrium-90,[2] a radioisotope which destroys the tumour cells.

The drug was developed by Immunomedics, Inc.

References

  1. ^ "Statement On A Nonproprietary Name Adopted By The USAN Council: Yttrium Y90 clivatuzumab tetraxetan". American Medical Association. http://www.ama-assn.org/ama1/pub/upload/mm/365/yttrium-Y-90-clivatuzumab-tetraxetan.pdf. 
  2. ^ WHO Drug Information
v · d · eMonoclonal antibodies for tumors
Tumor ("-t(u[m])-")
Human ("-tumu-")

Adecatumumab • Belimumab • Cixutumumab • Conatumumab • Daratumumab • Drozitumab • Figitumumab • Ganitumab • Glembatumumab vedotin • Intetumumab • Iratumumab • Lexatumumab • Lucatumumab • Mapatumumab • Narnatumab • Necitumumab • Ofatumumab • Olaratumab • Panitumumab • Pritumumab • Radretumab • Rilotumumab • Robatumumab • Teprotumumab • Votumumab • Zalutumumab

"-melu-" (melanoma): Flanvotumab
Mouse ("-tumo-")

Altumomab pentetate • Anatumomab mafenatox • Arcitumomab • Bectumomab • Blinatumomab • CC49 • Detumomab • Ibritumomab tiuxetan • Minretumomab • Mitumomab • Moxetumomab pasudotox • Naptumomab estafenatox • Nofetumomab merpentan • Pemtumomab† • Pintumomab • Racotumomab • Satumomab pendetide • Taplitumomab paptox • Tenatumomab • Tositumomab • 3F8

"-govo-" (ovarian tumor): Abagovomab • Igovomab • Oregovomab

"-pro-" (prostate tumor): Capromab pendetide

"-colo-" (colonic tumor): Edrecolomab • Nacolomab tafenatox
Chimeric ("-tuxi-")

Amatuximab • Bavituximab • Brentuximab vedotin • Cetuximab • Ensituximab • Girentuximab • Indatuximab ravtansine • Rituximab • Siltuximab • Ublituximab

"-mexi-" (melanoma): Ecromeximab
Humanized ("-tuzu-")
Afutuzumab • Alemtuzumab • Bevacizumab • Bivatuzumab mertansine • Cantuzumab mertansine • Cantuzumab ravtansine • Citatuzumab bogatox • Clivatuzumab tetraxetan • Dacetuzumab • Dalotuzumab • Elotuzumab† • Etaracizumab • Farletuzumab • Ficlatuzumab • Gemtuzumab ozogamicin • Inotuzumab ozogamicin • Labetuzumab • Lintuzumab • Lorvotuzumab mertansine • Matuzumab§ • Milatuzumab • Nimotuzumab • Onartuzumab • Oportuzumab monatox • Pertuzumab • Sibrotuzumab • Tacatuzumab tetraxetan • Tigatuzumab • Trastuzumab • Tucotuzumab celmoleukin • Veltuzumab
Rat/mouse hybrid ("-tumaxo-")


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