- Zucapsaicin
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Zucapsaicin Systematic (IUPAC) name (Z)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide Clinical data Trade names Civanex Pregnancy cat. ? Legal status ? Routes Topical Identifiers CAS number 25775-90-0 ATC code M02AB02 PubChem CID 1548942 UNII 15OX67P384 Synonyms Civamide; (Z)-Capsaicin; cis-Capsaicin Chemical data Formula C18H27NO3 Mol. mass 305.41188 g/mol SMILES eMolecules & PubChem Zucapsaicin (Civanex) is a medication used to treat osteoarthritis of the knee and other neuropathic pain. It is the cis-isomer of capsaicin. Civamide, manufactured by Winston Pharmaceuticals, is produced in formulations for oral, nasal, and topical use (patch and cream). [1]
Zucapsaicin has been tested for treatment of a variety of conditions associated with ongoing nerve pain. This includes herpes simplex infections; cluster headaches and migraine; and knee osteoarthritis[2].
References
- ^ Winston Pharmaceuticals website http://www.winstonlabs.com/productdevelopment/civamide.asp
- ^ Zucapsaicin information from the National Library of Medicine http://druginfo.nlm.nih.gov/drugportal
Topical products for joint and muscular pain (M02) Anti-inflammatory preparations,
non-steroidsAcetic acid derivativesOtherBenzydamine • Etofenamate • Piroxicam • Felbinac • Bufexamac • Ketoprofen • Bendazac • Naproxen • Ibuprofen • Feprazone • Niflumic acid • Meclofenamic acid • Flurbiprofen • Suxibuzone • Indometacin • NifenazoneCapsaicin derivatives ZucapsaicinOther Tolazoline • Dimethyl sulfoxide • IdrocilamideCategories:- Musculoskeletal system drug stubs
- Drugs acting on the musculoskeletal system
- Capsaicinoids
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