DNPEP

DNPEP
Aspartyl aminopeptidase
Identifiers
Symbols DNPEP; ASPEP; DAP
External IDs OMIM611367 MGI1278328 HomoloGene6110 GeneCards: DNPEP Gene
EC number 3.4.11.21
RNA expression pattern
PBB GE DNPEP 38703 at tn.png
PBB GE DNPEP 201937 s at tn.png
PBB GE DNPEP 217604 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 23549 13437
Ensembl ENSG00000123992 ENSMUSG00000026209
UniProt Q9ULA0 Q3TVK3
RefSeq (mRNA) NM_012100 NM_016878
RefSeq (protein) NP_036232 NP_058574
Location (UCSC) Chr 2:
220.24 – 220.59 Mb
Chr 1:
75.3 – 75.31 Mb
PubMed search [1] [2]

Aspartyl aminopeptidase is an enzyme that in humans is encoded by the DNPEP gene.[1][2]

The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of intracellular proteins.[2]

References

  1. ^ Wilk S, Wilk E, Magnusson RP (Aug 1998). "Purification, characterization, and cloning of a cytosolic aspartyl aminopeptidase". J Biol Chem 273 (26): 15961–70. doi:10.1074/jbc.273.26.15961. PMID 9632644. 
  2. ^ a b "Entrez Gene: DNPEP aspartyl aminopeptidase". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23549. 

Further reading

External Links

  • The MEROPS online database for peptidases and their inhibitors: M18.002

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