Nervonic acid

Nervonic acid[1]
IUPAC name (Z)-Tetracos-15-enoic acid
Other names cis-15-Tetracosenoic acid 24:1 cis, delta 9 or 24:1 omega 9
Identifiers
CAS number	506-37-6 Y
PubChem	5281120
ChemSpider	4444565 Y
KEGG	C08323 Y
ChEBI	CHEBI:44247 N
ChEMBL	CHEMBL1173379 Y
Jmol-3D images	Image 1
SMILES O=C(O)CCCCCCCCCCCCC\C=C/CCCCCCCC
InChI InChI=1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9- Y Key: GWHCXVQVJPWHRF-KTKRTIGZSA-N Y InChI=1/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9- Key: GWHCXVQVJPWHRF-KTKRTIGZBL
Properties
Molecular formula	C24H46O2
Molar mass	366.62 g/mol
Melting point	42-43 °C
N acid (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Nervonic acid is a monounsaturated omega-9 fatty acid. Nervonic acid has been identified as important in the biosynthesis of nerve cell myelin.^[2] It is found in the sphingolipids of white matter in human brain.

Nervonic acid is used in the treatment of disorders involving demyelination, such as adrenoleukodystrophy and multiple sclerosis where there is a decreased level of nervonic acid in sphingolipids.^[3]

Notes

1. ^ Nervonic acid at Sigma-Aldrich
2. ^ US Patent 6664406, Nervonic acid derivatives, their preparation and use
3. ^ WO/1996/005740, Nervonic Acid Compositions

Additional references

• Appelqvist (1976) Lipids in Cruciferae. In: Vaughan JG, Macleod AJ (Eds), The biology and the Chemistry of Cruciferae. Academic Press, London, UK, pp. 221-277.
• Sargent JR, Coupland K, Wilson R (1994). Nervonic Acid and Demyelinating Disease. Medical Hypothesese 42, pp. 237-242.

This article about an organic compound is a stub. You can help Wikipedia by expanding it.v · Categories: Fatty acids Organic compound stubs Wikimedia Foundation. 2010. Игры ⚽ Нужно решить контрольную? Universidad Autónoma de Yucatán Front for the Liberation of the Golan Look at other dictionaries: nervonic acid — nervono rūgštis statusas T sritis chemija formulė H(CH₂)₈CH=CH(CH₂)₁₃COOH atitikmenys: angl. nervonic acid rus. нервоновая кислота ryšiai: sinonimas – 15 tetrakozeno rūgštis …   Chemijos terminų aiškinamasis žodynas nervonic acid — (ˈ)nər|vänik noun Etymology: nervonic International Scientific Vocabulary nervon + ic : a crystalline unsaturated fatty acid C23H45COOH obtained from nervon by hydrolysis and also found in some fish liver oils called also selacholeic acid …   Useful english dictionary nervonic acid — A 24 carbon straight chain fatty acid unsaturated between C 15 and C 16; occurs in cerebrosides such as nervone. * * * ner·von·ic acid nər .vän ik n a crystalline unsaturated fatty acid C23H45COOH obtained from nervon by hydrolysis * * *… …   Medical dictionary nervonic acid — noun The unsaturated fatty acid tetracosa 9 enoic acid that is a constituent of cerebrosides such as nervon …   Wiktionary nervonic — adjective Of or pertaining to nervonic acid or its derivatives …   Wiktionary Omega-9 fatty acid — For an explanation of n and numerical nomenclature (such as n−9 or 18:1), see Fatty acid#Nomenclature. Types of fats in food Unsaturated fat Monounsaturated fat Polyunsaturated fat Trans fat Cis fat Omega fatty acids: ω−3 ω−6 ω−9 Saturated fat… …   Wikipedia fatty acid — noun Any of a class of aliphatic carboxylic acids, of general formula CHCOOH, that occur combined with glycerol as animal or vegetable oils and fats. Only those with an even number of carbon atoms are normally found in …   Wiktionary selacholeic acid — |selə(ˌ) kō|lēik , ˌ ̷ ̷ ̷ ̷ˈkōˌlēik noun Etymology: selacholeic from Greek selachos cartilaginous fish + oleic; from its being found in some fish liver oils : nervonic acid …   Useful english dictionary Acetic acid — Acetic redirects here. It is not to be confused with Ascetic. Acetic acid …   Wikipedia Fatty acid — Not to be confused with fat. Butyric acid, a short chain fatty acid Types of fats in food Unsaturated fat Monounsaturated fat Polyun …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”