Drostanolone propionate

Dromostanolone

Systematic (IUPAC) name
(2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
Clinical data
Pregnancy cat.	X
Legal status	Schedule IV (CA) Schedule III (US)
Routes	Intramuscular injection or transdermal cream
Pharmacokinetic data
Bioavailability	Oral 0-2%, Intramuscular 100%
Protein binding	highly
Metabolism	hepatic
Half-life	2-3 Days
Excretion	renal
Identifiers
CAS number	58-19-5
ATC code	A14
PubChem	CID 224004
DrugBank	DB00858
ChemSpider	194604 Y
ChEBI	CHEBI:31523 Y
Chemical data
Formula	C23H36O3
Mol. mass	360.53 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C23H36O3/c1-5-21(25)26-20-9-8-17-16-7-6-15-12-19(24)14(2)13-23(15,4)18(16)10-11-22(17,20)3/h14-18,20H,5-13H2,1-4H3/t14-,15+,16+,17+,18+,20+,22+,23+/m1/s1 Y Key:NOTIQUSPUUHHEH-UXOVVSIBSA-N Y
Y(what is this?)  propionate (verify)

Drostanolone propionate (trade name Masteron) is an anabolic/androgenic steroid which is the propionate ester of drostanolone. It is known to be highly androgenic and mildly anabolic.^{[citation needed]} It is incapable of aromatization and has similar properties to dihydrotestosterone.^{[citation needed]} It has been successfully used as a breast cancer drug, but because of the high risk of virilization, safer options are prescribed.^[1]

Use in sports

Drostanolone propionate is used primarily by athletes who need to retain strength while losing mass. It is beneficial to runners and athletes who must remain in a certain weight class.^{[citation needed]}

It has gained popularity in the bodybuilding community as a diuretic and muscle defining drug. Individuals interested in using the drostanolone propionate are those that are looking to add muscle hardness and density to their physiques, nearly always for the purpose of bodybuilding competitions.^{[citation needed]}

Drostanolone propionate can increase muscle hardness and density, giving an individual a more complete appearance when competing on stage.^{[citation needed]} However, an already rather low body-fat level is needed for it to take full effect.^{[citation needed]} Drostanolone propionate can promote increased strength while keeping body fat the same or even lowering it, something can help to prevent muscle loss while dieting.^{[citation needed]} This can also allow strength athletes or those athletes in sports which have weight classes to increase performance without the risk of being raised into a higher weight class or add mass that may hinder performance.^{[citation needed]}

References

1. ^ Chowdhury MS, Banks AJ, Bond WH, Jones WG, Ward HW (1976). "A comparison of drostanolone propionate (Masteril) and nandrolone decanoate (Deca-durabolin) in the treatment of breast carcinoma". Clin Oncol 2 (3): 203–6. PMID 103698.