Dimethylthiambutene

Dimethylthiambutene

Systematic (IUPAC) name
(RS)-N,N-dimethyl-4,4-dithiophen-2-yl-but-3-en-2-amine
Clinical data
Pregnancy cat.	?
Legal status	Schedule I (US)
Identifiers
CAS number	524-84-5
ATC code	None
PubChem	CID 10668
DrugBank	DB01444
ChemSpider	10218 Y
UNII	915D88LM9O Y
ChEBI	CHEBI:59781 Y
Chemical data
Formula	C14H17NS2
Mol. mass	263.424 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C14H17NS2/c1-11(15(2)3)10-12(13-6-4-8-16-13)14-7-5-9-17-14/h4-11H,1-3H3 Y Key:CANBGVXYBPOLRR-UHFFFAOYSA-N Y
Physical data
Melt. point	169–170 °C (336–338 °F)
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Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Ohton, Aminobutene, Dimethibutin, Kobaton, Takaton, Dimethibutin) is an opioid analgesic drug, most often used in veterinary medicine in Japan and to a lesser extent in other countries in the region and around the world. It is the most prominent and widely-used of the thiambutenes, a series of open-chain opioids structurally related to methadone which are also called the thienyl derivative opioids which also includes diethylthiambutene and ethylmethylthiambutene as well as the cough suppressant tipepidine, which is weaker and not a controlled substance in most of the world.

Dimethylthiambutene was developed in the United States in the early 1950s and introduced to the market by Burroughs-Wellcome in the United Kingdom in 1951. Dimethylthiambutene is now under international control under the UN Single Convention on Narcotic Drugs 1961, the laws governing habit-forming substances in virtually all countries and Schedule I of the US Controlled Substances Act of 1970 due to high abuse potential and never being introduced clinically in the United States; other countries regulate it much as morphine or diamorphine.

This analgesic-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Synthetic opioids Thiophenes Amines Mu-opioid agonists Analgesic stubs Wikimedia Foundation. 2010. Игры ⚽ Нужно сделать НИР? HIVE (virtual environment) Kathleen Mead Look at other dictionaries: dimethylthiambutene — noun A particular narcotic painkiller …   Wiktionary Opioid — Endogenous opioid peptides Skeletal molecular images Adrenorphin Amidorphin Casomorphin …   Wikipedia Thiambutene — drugbox IUPAC name = 4,4 dithiophen 2 yl but 3 en 2 amine width = 140 CAS number = ATC prefix = ATC suffix = PubChem = C=12 | H=13 | N=1 | S=2 molecular weight = 235.368 g/mol smiles = s1cccc1C(=CC(N)C)c2sccc2 melting point = 174 melting high =… …   Wikipedia Morphine — This article is about the drug. For other meanings, see Morphine (disambiguation). Morphia redirects here. For other uses, see Morphia (disambiguation). Not to be confused with Morphinae, Morphea, or Morpholine. Morphine …   Wikipedia Opiate — For other uses see Opiate (disambiguation), or for the class of drugs see Opioid. Harvesting the poppy pod. In medicine, the term opiate describes any of the narcotic opioid alkaloids found as natural products in the opium poppy plant …   Wikipedia Phencyclidine — Systematic (IUPAC) name …   Wikipedia Loperamide — Imodium redirects here. For the song by Nirvana, see Breed (song). Loperamide Systematic (IUPAC) name …   Wikipedia Pethidine — Systematic (IUPAC) name …   Wikipedia Opioid receptor — Opioid receptors are a group of G protein coupled receptors with opioids as ligands.[1][2][3] The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are 40% identical to somatostatin… …   Wikipedia Oxymorphone — Systematic (IUPAC) name 4,5α epoxy 3,14 dihydroxy 17 methylmorphinan 6 one Clinical data Trade names …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”