Classification and external resources
ICD-10 K14.6
ICD-9 529.4, 529.6
MeSH D005926

Glossodynia or burning mouth syndrome (BMS) (also known as "Burning tongue"[1] and "Orodynia"[2]) is a condition characterized by a burning or tingling sensation on the lips, tongue, or entire mouth.

Typically, there are no visual signs like discoloration that help the diagnosis.



Possible causes include nutritional deficiencies, chronic anxiety or depression, type 2 diabetes, menopause, oral disorders such as thrush or dry mouth, or damaged nerves (specifically, cranial nerves associated with taste).

One cause of burning mouth pain, which may be often misdiagnosed as burning mouth syndrome, is a contact sensitivity Type IV hypersensitivity in the oral tissues to common substances such as sodium lauryl sulfate, a surfactant commonly used in household products, cinnamon aldehyde or dental materials. There are now several toothpastes on the market specifically without sodium lauryl sulfate or other preservatives which have been found to be associated with sensitivities.[1]


This condition appears more often in women, specifically women after menopause, than men. Pain typically is low or nonexistent in the morning and builds up over the course of the day.


Low dosages of benzodiazepines, tricyclic antidepressants or anticonvulsants may prove to be an effective treatment.

Alpha-lipoic acid 600 to 800 mg administered daily in three or four doses has been found to reduce symptoms. Trials have been small, but alpha-lipoic acid may be an appropriate adjunctive treatment option.

See also


  1. ^ a b James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. p. 63. ISBN 0-7216-2921-0. 
  2. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0. 
  • De Rossi SS, Greenberg MS (October 1998). "Intraoral contact allergy: a literature review and case reports". J Am Dent Assoc 129 (10): 1435–41. PMID 9787540. 

External links