Bemegride

Bemegride

Systematic (IUPAC) name
4-ethyl-4-methylpiperidine-2,6-dione
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	64-65-3
ATC code	R07AB05
PubChem	CID 2310
ChemSpider	2220 Y
UNII	57DQA39DO2 Y
KEGG	D01957 Y
ChEMBL	CHEMBL1214192 Y
Synonyms	Methetharimide β,β-methylethylglutarimide
Chemical data
Formula	C8H13NO2
Mol. mass	155.194 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C8H13NO2/c1-3-8(2)4-6(10)9-7(11)5-8/h3-5H2,1-2H3,(H,9,10,11) Y Key:ORRZGUBHBVWWOP-UHFFFAOYSA-N Y
Y(what is this?)  (verify)

Bemegride (also known as Megimide) is a central Nervous System stimulant and antidote for barbiturate poisoning.

John Bodkin Adams case

For more details on this topic, see John Bodkin Adams#Gertrude Hullett.

Bemegride is notable in legal history as the drug suspected serial killer Dr John Bodkin Adams failed to prescribe correctly to his patient Gertrude Hullett. Hullett took an overdose of barbiturates on 19 July 1956 but Adams only gave her a single 10cc dose of bemegride three days later on the 22nd, despite having acquired 100cc for her treatment. Hullett died the next day on 23 July 1956. Adams was charged but never tried for her murder.^[1]

Animal use

Bemegride is also used to induce convulsions in experimental animals.^[2]

References

1. ^ Cullen, Pamela V., A Stranger in Blood: The Case Files on Dr John Bodkin Adams, London, Elliott & Thompson, 2006, ISBN 1-904027-19-9
2. ^ Definition: bemegride from Online Medical Dictionary

This drug article relating to the respiratory system is a stub. You can help Wikipedia by expanding it.v · Categories: Antidotes Stimulants Respiratory agents Convulsants Glutarimides Respiratory system drug stubs Wikimedia Foundation. 2010. Игры ⚽ Нужна курсовая? MSDN Blogs Danny Weinkauf Look at other dictionaries: bemegride — noun A central nervous system stimulant and antidote for barbiturate poisoning …   Wiktionary bemegride — A central nervous system stimulant formerly used as an analeptic in intoxications due to barbiturates and other central nervous system depressant drugs. * * * be·me·gride bem ə .grīd, bē mə n an analeptic drug C18H13NO2 used esp. to counteract… …   Medical dictionary bemegride — be·me·gride …   English syllables bemegride — ˈbeməˌgrīd, ēm noun ( s) Etymology: beta + ethyl + methyl + glutalric acid + imide : an analeptic drug C8H13NO2 used especially to counteract the effect of barbiturates …   Useful english dictionary Amiphenazole — Systematic (IUPAC) name 5 phenyl 1,3 thiazole 2,4 diamine Clinical data Pregnancy cat.  ? …   Wikipedia Primidone — Systematic (IUPAC) name 5 ethyl 5 phenyl hexahydropyrimidine 4,6 dione Clinical data Pregnancy cat. D …   Wikipedia Aminorex — Systematic (IUPAC) name (RS) 5 phenyl 4,5 dihydro 1,3 oxazol 2 amine Clinical data Pregnancy cat.  …   Wikipedia Бемегрид — (Bemegride) Химическое соединение …   Википедия Convulsant — A convulsant is a drug which induces convulsions and/or epileptic seizures, the opposite of an anticonvulsant. These drugs generally act as stimulants at low doses, but are not used for this purpose due to the risk of convulsions and consequent… …   Wikipedia Amphetamine — For other uses, see Amphetamine (disambiguation). Amphetamine Systematic (IUPAC) name …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”