Terminator (genetics)

Terminator (genetics)

In genetics, a terminator, or transcription terminator is a section of genetic sequence that marks the end of gene or operon on genomic DNA for transcription.

In prokaryotes, two classes of transcription terminators are known:

  1. Intrinsic transcription terminators where a hairpin structure forms within the nascent transcript that disrupts the mRNA-DNA-RNA polymerase ternary complex.
  2. Rho-dependent transcription terminators that require Rho factor, an RNA helicase protein complex, to disrupt the nascent mRNA-DNA-RNA polymerase ternary complex.

In eukaryotes, terminators are recognized by protein factors

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v · Transcription (Prokaryotic, Eukaryotic)
Transcriptional regulation
prokaryotic
eukaryotic
both
Promotion
Initiation (prokaryotic,
eukaryotic)
Transcription start site
Elongation
Termination
(prokaryotic,
eukaryotic)
see also disorders of transcription and post transcriptional modification
B bsyn: dna (repl, cycl, reco, repr) · tscr (fact, tcrg, nucl, rnat, rept, ptts) · tltn (risu, pttl, nexn) · dnab, rnab/runp · stru (domn, 1°, 2°, 3°, 4°)

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