Chromatin remodeling

Chromatin remodeling is the enzyme-assisted movement of nucleosomes on DNA.

This is performed by chromatin remodeling complexes like SWI/SNF^[1] (human, yeast), RSC (yeast) and Imitation SWI complexes (fly).

At the core of a chromatin remodeling complex is an ATPase capable of DNA translocation.

By moving nucleosomes, proteins like transcription factors can get access to DNA that was previously unavailable, wrapped around nucleosome cores.^[2]

External links

• MeSH Chromatin+remodeling

References

1. ^ Harvey F. Lodish (2008). Molecular cell biology. St. Martin's Press. pp. 306–. ISBN 9780716776017. http://books.google.com/books?id=K3JbjG1JiUMC&pg=PA306. Retrieved 26 December 2010. 
2. ^ Saha A, Wittmeyer J, Cairns BR (2006). "Chromatin remodelling: the industrial revolution of DNA around histones". Nat Rev Mol Cell Biol 7 (6): 437–47. doi:10.1038/nrm1945. PMID 16723979. 

Promotion

Promoter (Pribnow box, TATA box, BRE, CAAT box, Response element) · Enhancer (E-box, Response element) · Insulator · Silencer

Initiation (prokaryotic,
eukaryotic)

Transcription start site

Elongation

prokaryotic RNA polymerase: rpoB

eukaryotic RNA polymerase: RNA polymerase II

Termination
(prokaryotic,
eukaryotic)

Terminator · Intrinsic termination · Rho factor

see also disorders of transcription and post transcriptional modification
B bsyn: dna (repl, cycl, reco, repr) · tscr (fact, tcrg, nucl, rnat, rept, ptts) · tltn (risu, pttl, nexn) · dnab, rnab/runp · stru (domn, 1°, 2°, 3°, 4°)