- SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2, also known as SMARCC2, is a human
gene .cite web | title = Entrez Gene: SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6601| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Two transcript variants encoding different isoforms have been found for this gene.cite web | title = Entrez Gene: SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6601| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Wang W, Xue Y, Zhou S, "et al." |title=Diversity and specialization of mammalian SWI/SNF complexes. |journal=Genes Dev. |volume=10 |issue= 17 |pages= 2117–30 |year= 1996 |pmid= 8804307 |doi=
*cite journal | author=Wang W, Côté J, Xue Y, "et al." |title=Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. |journal=EMBO J. |volume=15 |issue= 19 |pages= 5370–82 |year= 1996 |pmid= 8895581 |doi=
*cite journal | author=Wang W, Chi T, Xue Y, "et al." |title=Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 2 |pages= 492–8 |year= 1998 |pmid= 9435219 |doi=
*cite journal | author=Ring HZ, Vameghi-Meyers V, Wang W, "et al." |title=Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome. |journal=Genomics |volume=51 |issue= 1 |pages= 140–3 |year= 1998 |pmid= 9693044 |doi= 10.1006/geno.1998.5343
*cite journal | author=Cho H, Orphanides G, Sun X, "et al." |title=A human RNA polymerase II complex containing factors that modify chromatin structure. |journal=Mol. Cell. Biol. |volume=18 |issue= 9 |pages= 5355–63 |year= 1998 |pmid= 9710619 |doi=
*cite journal | author=Phelan ML, Sif S, Narlikar GJ, Kingston RE |title=Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits. |journal=Mol. Cell |volume=3 |issue= 2 |pages= 247–53 |year= 1999 |pmid= 10078207 |doi=
*cite journal | author=Bochar DA, Wang L, Beniya H, "et al." |title=BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer. |journal=Cell |volume=102 |issue= 2 |pages= 257–65 |year= 2000 |pmid= 10943845 |doi=
*cite journal | author=Kadam S, McAlpine GS, Phelan ML, "et al." |title=Functional selectivity of recombinant mammalian SWI/SNF subunits. |journal=Genes Dev. |volume=14 |issue= 19 |pages= 2441–51 |year= 2000 |pmid= 11018012 |doi=
*cite journal | author=Xue Y, Canman JC, Lee CS, "et al." |title=The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 24 |pages= 13015–20 |year= 2001 |pmid= 11078522 |doi= 10.1073/pnas.240208597
*cite journal | author=Sif S, Saurin AJ, Imbalzano AN, Kingston RE |title=Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes. |journal=Genes Dev. |volume=15 |issue= 5 |pages= 603–18 |year= 2001 |pmid= 11238380 |doi= 10.1101/gad.872801
*cite journal | author=Kato H, Tjernberg A, Zhang W, "et al." |title=SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones. |journal=J. Biol. Chem. |volume=277 |issue= 7 |pages= 5498–505 |year= 2002 |pmid= 11734557 |doi= 10.1074/jbc.M108702200
*cite journal | author=Battaglioli E, Andrés ME, Rose DW, "et al." |title=REST repression of neuronal genes requires components of the hSWI.SNF complex. |journal=J. Biol. Chem. |volume=277 |issue= 43 |pages= 41038–45 |year= 2002 |pmid= 12192000 |doi= 10.1074/jbc.M205691200
*cite journal | author=Olave I, Wang W, Xue Y, "et al." |title=Identification of a polymorphic, neuron-specific chromatin remodeling complex. |journal=Genes Dev. |volume=16 |issue= 19 |pages= 2509–17 |year= 2002 |pmid= 12368262 |doi= 10.1101/gad.992102
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Nie Z, Yan Z, Chen EH, "et al." |title=Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner. |journal=Mol. Cell. Biol. |volume=23 |issue= 8 |pages= 2942–52 |year= 2003 |pmid= 12665591 |doi=
*cite journal | author=Kitagawa H, Fujiki R, Yoshimura K, "et al." |title=The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. |journal=Cell |volume=113 |issue= 7 |pages= 905–17 |year= 2003 |pmid= 12837248 |doi=
*cite journal | author=Hsiao PW, Fryer CJ, Trotter KW, "et al." |title=BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation. |journal=Mol. Cell. Biol. |volume=23 |issue= 17 |pages= 6210–20 |year= 2003 |pmid= 12917342 |doi=
*cite journal | author=Bouwmeester T, Bauch A, Ruffner H, "et al." |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086
*cite journal | author=Kuwabara T, Hsieh J, Nakashima K, "et al." |title=A small modulatory dsRNA specifies the fate of adult neural stem cells. |journal=Cell |volume=116 |issue= 6 |pages= 779–93 |year= 2004 |pmid= 15035981 |doi=
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101PBB_Controls
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