Alglucerase

Alglucerase

Systematic (IUPAC) name
Human beta-glucocerebrosidase
Clinical data
AHFS/Drugs.com	monograph
MedlinePlus	a692001
Pregnancy cat.	?
Legal status	?
Pharmacokinetic data
Half-life	3.6–10.4 min
Identifiers
CAS number	37228-64-1 Y
ATC code	A16AB01
DrugBank	BTD00037
UNII	27T56C7KK0 Y
KEGG	D09675 Y
ChEMBL	CHEMBL1201633 N
Chemical data
Formula	C2532H3854N672O711S16
Mol. mass	55597.4 g/mol
N(what is this?)  (verify)

Alglucerase is a modified form of human β-glucocerebrosidase where the non-reducing ends of the oligosaccharide chains have been terminated with mannose residues. Ceredase is the trade name of a citrate buffered solution of alglucerase manufactured by Genzyme Corporation from human placental tissue. It is given intravenously in the treatment of Type 1 Gaucher's disease although it has been largely replaced by imiglucerase which is produced by recombinant DNA technology.^{[citation needed]}

External links

• Ceredase page at Harvard's Gaucher Treatment Program

This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it.v · Categories: Hydrolases Gastrointestinal system drug stubs Wikimedia Foundation. 2010. Игры ⚽ Нужна курсовая? Étienne de Besançon Our Kids Our Future Look at other dictionaries: alglucerase — al·glu·ce·rase .al glü sə .rās n modified human glucocerebrosidase administered for enzyme replacement therapy in the treatment of Gaucher s disease see ceredase * * * al·glu·cer·ase (al glooґsər ās″) a modified form of β… …   Medical dictionary Ceredase — Cer·e·dase ser ə .dās trademark used for a preparation of alglucerase * * * Cer·e·dase (serґə dās) trademark for a preparation of alglucerase …   Medical dictionary Carnitine — Systematic (IUPAC) name 3 hydroxy 4 (trimethylazaniumyl)butanoate Clinical data AHFS/Drugs.com …   Wikipedia ATC code A16 — is a division of the Anatomical Therapeutic Chemical Classification System and part of the A Alimentary tract and metabolism section.A16A Other alimentary tract and metabolism products*A16AA Amino acids and derivatives:A16AA01… …   Wikipedia Tetrahydrobiopterin — Systematic (IUPAC) name (6R) 2 Amino 6 [(1R,2S) 1,2 dihydroxypropyl] 5,6,7,8 tetrahydropteridin 4(1H) one Clinical data …   Wikipedia Imiglucerase — Systematic (IUPAC) name Human Beta glucocerebrosidase Clinical data AHFS/Drugs.com monograph MedlinePlus …   Wikipedia Nitisinone — Systematic (IUPAC) name 2 [2 nitro 4 (trifluoromethyl)benzoyl] cyclohexane 1,3 dione Clinical data AHFS/Drugs.com …   Wikipedia Miglustat — Systematic (IUPAC) name (2R,3R,4R,5S) 1 butyl 2 (hydroxymethyl)piperidine 3,4,5 triol Clinical data AHFS/Drugs.co …   Wikipedia Alglucosidase alfa — Systematic (IUPAC) name Human glucosidase, prepro α [199 arginine,223 histidine] [1] Clinical data AHFS/Drugs.com …   Wikipedia Enzyme replacement therapy — Die Enzymersatztherapie (EET oder ERT von engl. Enzyme Replacement Therapy) ist ein therapeutisches Verfahren zur Behandlung von Enzymdefekten bei lysosomalen Speicherkrankheiten. Den Patienten werden dabei per Infusion oder Injektion… …   Deutsch Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”