Idursulfase

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CAS_number = 50936-59-9
ATC_prefix = A16
ATC_suffix = AB09
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Idursulfase (brand name Elaprase) is a drug used to treat Hunter syndrome (also called Mucopolysaccharoidosis II).cite journal |author=Garcia AR, DaCosta JM, Pan J, Muenzer J, Lamsa JC |title=Preclinical dose ranging studies for enzyme replacement therapy with idursulfase in a knock-out mouse model of MPS II |journal=Mol. Genet. Metab. |volume=91 |issue=2 |pages=183–90 |year=2007 |pmid=17459751 |doi=10.1016/j.ymgme.2007.03.003] It is a purified form of the lysosomal enzyme iduronate-2-sulfatase and is produced by recombinant DNA technology in a human cell line.

It is one of the most expensive drugs ever produced. Initial yearly costs were reported to be $300,000. [cite web |url=http://www.cbc.ca/cp/health/060725/x072509.html |title=Drug approved to treat rare but potentially deadly disease |accessdate=2007-09-02 |format= |work=]

It is manufactured by Shire Pharmaceuticals Group.

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