o-Anisidine

o-Anisidine
IUPAC name 2-Methoxyaniline
Other names 2-anisidine, ortho-aminoanisole, o-methoxyaniline, 2-methoxy-1-aminobenzene, 2-methoxyphenylamine
Identifiers
CAS number	90-04-0 Y
ChemSpider	13860775 Y
EC-number	201-963-1
UN number	2431
KEGG	C19191 Y
Jmol-3D images	Image 1
SMILES Nc1ccccc1OC
InChI InChI=1S/C7H9NO/c1-9-7-5-3-2-4-6(7)8/h2-5H,8H2,1H3 Y Key: VMPITZXILSNTON-UHFFFAOYSA-N Y InChI=1/C7H9NO/c1-9-7-5-3-2-4-6(7)8/h2-5H,8H2,1H3
Properties[1]
Molecular formula	C7H9NO
Molar mass	123.15 g/mol
Appearance	yellow liquid turns brown upon exposure to air
Density	1.0923 g/cm3
Melting point	6.2 °C
Boiling point	224 °C
Solubility in water	1.5 g/100 ml
Solubility	soluble in ethanol, diethyl ether, acetone, benzene
Hazards
EU Index	612-035-00-4
EU classification	Toxic (T) Carc. Cat. 2 Muta. Cat. 3
R-phrases	R45, R23/24/25, R68
S-phrases	S53, S45
NFPA 704	1 2 0
Flash point	118 °C (open cup)
Autoignition temperature	415 °C
Related compounds
Related compounds	m-Anisidine p-Anisidine
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

o-Anisidine is a yellow liquid with melting point -1 to 5 °C and density 1.09 g/cm³. The vapor pressure is 0.05 mbar at 20 °C but increases greatly with temperature. It has an aromatic smell and is well absorbed by inhalation, oral ingestion and skin contact. 2-Anisidine is a very toxic agent that causes blood, enzyme and nerve damage with cyanosis and the danger of suffocation. The agent is an experimental carcinogen and is strongly suspected to be also a human carcinogen. 2-Anisidine has dangerous pollutant properties for water.

References

1. ^ Weast, Robert C., ed (1981). CRC Handbook of Chemistry and Physics (62nd ed.). Boca Raton, FL: CRC Press. p. C-98. ISBN 0-8493-0462-8. .

External links

• International Chemical Safety Card 0970
• NIOSH Pocket Guide to Chemical Hazards 0034