Dukes' disease

Dukes' disease
Fourth disease
Classification and external resources
ICD-10 B09
ICD-9 057.8

Dukes' disease or fourth disease is an exanthem.

It is named for Clement Dukes.[1][2]

Some of these eruptions are characteristic of the causative virus, but in most cases one must be satisfied with the diagnosis of viral rash.

It was never associated with a specific pathogen,[3] and the terms "fourth disease" and "Dukes' disease" are rarely used today.

In 1979 Keith Powell proposed equating it with the condition currently known as Staphylococcal scalded skin syndrome.[4][5]

Presentation

Signs and symptoms may include fever, nausea, vomiting, and diarrhea, along with typical viral symptoms of photophobia, lymphadenopathy, sore throat, and possibly encephalitis. The rash may appear at any time during the illness. It is usually generalised. The rash consists of erythematous maculopapules with areas of confluence. They may be urticarial, vesicular, or sometimes petechial. The palms and soles may be involved. The eruptions are more common in children than in adults. Usually, the rash fades without pigmentation or scaling.

References

  1. ^ Dukes-Filatov disease at Who Named It?
  2. ^ C. Dukes: On the confusion of two different diseases under the name of rubella (rose-rash). Lancet, London, 1900, 2: 89-94.
  3. ^ Morens DM, Katz AR (September 1991). "The "fourth disease" of childhood: reevaluation of a nonexistent disease". Am. J. Epidemiol. 134 (6): 628–40. PMID 1951267. http://aje.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=1951267. 
  4. ^ Weisse ME (January 2001). "The fourth disease, 1900-2000". Lancet 357 (9252): 299–301. doi:10.1016/S0140-6736(00)03623-0. PMID 11214144. http://linkinghub.elsevier.com/retrieve/pii/S0140-6736(00)03623-0. 
  5. ^ Powell KR (January 1979). "Filatow-Dukes' disease. Epidermolytic toxin-producing staphylococci as the etiologic agent of the fourth childhood exanthem". Am. J. Dis. Child. 133 (1): 88–91. PMID 367152. 
v · d · eInfectious skin disease: Viral cutaneous conditions, including viral exanthema (B00–B09, 050–059)
HSV (Herpes simplex, Herpetic whitlow, Herpes gladiatorum, Herpetic keratoconjunctivitis, Herpetic sycosis, Neonatal herpes simplex, Herpes genitalis, Herpes labialis, Eczema herpeticum, Herpetiform esophagitis) · Herpes B virus (B virus infection)
Human herpesvirus 6/Roseolovirus (Exanthema subitum, Roseola vaccinia)
Variola (Smallpox, Eczema vaccinatum, Alastrim) · MoxV (Monkeypox) · CV (Cowpox) · VV (Vaccinia, Generalized vaccinia, Progressive vaccinia)
Sealpox
Other
Yatapoxvirus: Tanapox · Yaba monkey tumor virus
Papillomaviridae
HPV (Wart/Plantar wart, Heck's disease, Genital wart (giant), Laryngeal papillomatosis, Butcher's wart, Bowenoid papulosis, Epidermodysplasia verruciformis, Verruca plana, Pigmented wart, Verrucae palmares et plantares )
BPV (Equine sarcoid)
Parvovirus B19 (Erythema infectiosum, Reticulocytopenia, Papular purpuric gloves and socks syndrome)
CAV (Hand, foot and mouth disease, Herpangina) · FMDV (Foot-and-mouth disease) · Boston exanthem disease
Ungrouped
unknown/multiple: Asymmetric periflexural exanthem of childhood · Post-vaccination follicular eruption · Lipschütz ulcer · Eruptive pseudoangiomatosis · Viral-associated trichodysplasia · Gianotti–Crosti syndrome

M: VIR

virs(prot)/clss

cutn/syst (hppv/hiva, infl/zost/zoon)/epon

drugJ(dnaa, rnaa, rtva, vacc)

M: INT, SF, LCT

anat/phys/devp

noco(i/b/d/q/u/r/p/m/k/v/f)/cong/tumr(n/e/d), sysi/epon

proc, drug (D2/3/4/5/8/11)

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