CPK-MB test

CPK-MB test
CPK-MB test
Diagnostics

Kinetics of cardiac markers in myocardial infarction with or without reperfusion treatment.
LOINC 49551-5, 51506-4, 2154-3, 13969-1, 32673-6, 38482-6

The CPK-MB test is a cardiac marker[1] used to assist diagnoses of an acute myocardial infarction. It measures the CKM and CKB isoenzymes of phosphocreatine kinase.

In some locations, the test has been superseded by the troponin test. However, recently, there have been improvements to the test that involve measuring the ratio of the CK-MB1 and CK-MB2 isoforms.[2]

The newer test detects different isoforms of the B subunit specific to the myocardium whereas the older test detected the presence of cardiac-related isoenzyme dimers.

References


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