Noxious stimulus

Noxious stimulus

A noxious stimulus is "an actually or potentially tissue damaging event."[1] It is a prerequisite for nociception, which itself is a prerequisite for nociceptive pain[1]

Noxious stimuli can either be mechanical (e.g. pinching or other tissue deformation), chemical (e.g. exposure to acid or irritant), or thermal (e.g. high or low temperatures).

There are some types of tissue damage that are not detected by any sensory receptors, and thus cannot cause pain. Therefore, not all noxious stimuli are adequate stimuli of nociceptors. The adequate stimuli of nociceptors are termed nociceptive stimuli. A nociceptive stimulus is defined as "an actually or potentially tissue damaging event transduced and encoded by nociceptors."[1]

References

  1. ^ a b c Loeser JD, Treede RD. (2008). "The Kyoto protocol of IASP Basic Pain Terminology.". Pain 137 (3): 473–7. doi:10.1016/j.pain.2008.04.025. PMID 18583048. 
v · d · ePain and nociception
By region/system
HEENT
Cardiovascular system
Sore throat · Pleurodynia
Musculoskeletal
Neurologic
Congenital insensitivity to pain · HSAN (Type I, II congenital sensory neuropathy, III familial dysautonomia, IV congenital insensitivity to pain with anhidrosis, V congenital insensitivity to pain with partial anhidrosis) · Neuralgia · Pain asymbolia · Pain disorder · Paroxysmal extreme pain disorder · Allodynia · Chronic pain · Hyperalgesia · Hypoalgesia · Hyperpathia · Phantom pain · Referred pain
Urogenital
Dysuria · Pelvic pain · Dyspareunia · Testicular pain
Gastrointestinal
Proctalgia
Upper · Lower
Tests
Related concepts

M: CNS

anat(n/s/m/p/4/e/b/d/c/a/f/l/g)/phys/devp

noco(m/d/e/h/v/s)/cong/tumr, sysi/epon, injr

proc, drug(N1A/2AB/C/3/4/7A/B/C/D)

M: PNS

anat(h/r/t/c/b/l/s/a)/phys(r)/devp/prot/nttr/nttm/ntrp

noco/auto/cong/tumr, sysi/epon, injr

proc, drug(N1B)

Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • Noxious — may refer to: Poison, substances that can can harm or kill . Noxious weed, a plant designated by the government as injurious to public health, agriculture, recreation, wildlife or property Noxious stimulus, an actually or potentially tissue… …   Wikipedia

  • stimulus — 1. A stimulant. 2. That which can elicit or evoke action (response) in a muscle, nerve, gland or other excitable tissue, or cause an augmenting action upon any function or metabolic …   Medical dictionary

  • Diffuse noxious inhibitory control — Diffuse Noxious Inhibitory Controls (DNIC) refers to an endogenous pain modulatory pathway which has often been described as pain inhibits pain .[1] It occurs when response from a painful stimulus is inhibited by another, often spatially distant …   Wikipedia

  • nervous system, human — ▪ anatomy Introduction       system that conducts stimuli from sensory receptors to the brain and spinal cord and that conducts impulses back to other parts of the body. As with other higher vertebrates, the human nervous system has two main… …   Universalium

  • animal behaviour — Introduction       any activity of an intact organism.       A living animal behaves constantly in order to survive, and all animals must solve the same basic problems. They must, for instance, periodically replace their energy source (consume… …   Universalium

  • Pain — This article is about physical pain. For pain in the broader sense, see Suffering. For other uses, see Pain (disambiguation). Pain A sports player in pain. ICD 10 R52 …   Wikipedia

  • Nociceptor — A nociceptor is a sensory receptor that responds to potentially damaging stimuli by sending nerve signals to the spinal cord and brain. This process, called nociception, usually causes the perception of pain. Contents 1 History 2 Location 3… …   Wikipedia

  • pain — /payn/, n. 1. physical suffering or distress, as due to injury, illness, etc. 2. a distressing sensation in a particular part of the body: a back pain. 3. mental or emotional suffering or torment: I am sorry my news causes you such pain. 4. pains …   Universalium

  • Group C nerve fiber — Infobox Anatomy Name = PAGENAME Latin = GraySubject = GrayPage = Caption = C fiber not labeled, but substantia gelatinosa of Rolando is Rexed lamina II, labeled at upper left. Caption2 = Precursor = System = Artery = Vein = Nerve = Lymph =… …   Wikipedia

  • Nociception assay — A Nociception assay (nocioception or nocioperception assay) evaluates the ability of an animal, usually a rodent, to detect a noxious stimulus such as the feeling of pain, caused by stimulation of nociceptors. These assays measure the existence… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”