4-Nitroquinoline 1-oxide

4-Nitroquinoline 1-oxide
IUPAC name 4-nitroquinoline 1-oxide
Identifiers
CAS number	56-57-5 Y
PubChem	5955
ChemSpider	5740 Y
KEGG	C03474 Y
ChEBI	CHEBI:16907 Y
ChEMBL	CHEMBL127655 Y
Jmol-3D images	Image 1
SMILES [O-][N+](=O)c2c1c(cccc1)[n+]([O-])cc2
InChI InChI=1S/C9H6N2O3/c12-10-6-5-9(11(13)14)7-3-1-2-4-8(7)10/h1-6H Y Key: YHQDZJICGQWFHK-UHFFFAOYSA-N Y InChI=1/C9H6N2O3/c12-10-6-5-9(11(13)14)7-3-1-2-4-8(7)10/h1-6H Key: YHQDZJICGQWFHK-UHFFFAOYAP
Properties
Molecular formula	C9H6N2O3
Molar mass	190.16 g mol−1
Hazards
Main hazards	causes DNA adducts. lactobacillus is being investigated for antigenotoxocity it causes.
Y 1-oxide (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

4-Nitroquinoline 1-oxide (also known as 4-NQO, 4NQO, 4Nqo, NQO and NQNO) is a quinoline derivative and a tumorigenic compound used in the assessment of the efficacy of diets, drugs, and procedures in the prevention and treatment of cancer in animal models. It induces DNA lesions usually corrected by nucleotide excision repair.

References

• 4-NQO in NCI Dictionary from PDQ (2004). Verified availability 2005-03-19.